Beruflich Dokumente
Kultur Dokumente
1, C
>>
IgM
Or PA2
>>
C
o >>
IgD
And both of them are going to be expressed on the surface, so the variable region
is the same in both & o. The difference in the C will have different functions.
What really decides for IgM to be secreted and stay on the surface of the B cell as
a B cell receptor also determined by the
gene expression.
If you look carefully, this is the surface
IgM. It has this green part of 2 parts, one
on the cytoplasmic membrane & one
inside the cell. Those (the green ones)
have to be coded by genes, while the
others as you can see they are the same.
So the difference on this
transmembrane section that's if that is
9
selected (T
m
1 & T
m
2
by stimulating PA
m
) it's going to be a surface, if it's not then
it's going to be secreted.
So if you look to here; the variable region is the same> same specificity, we have
then C