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CARDIO CONFERENCE
Calimag, Angela Parana, Rowena Y. Perlas, Carlo Queyquep, Valerie Joy G. Racoma, Jan Michael D. Ramos, NIna
I. GENERAL DATA
Name: JM Age: 9 Sex: Male Race: Filipino Birthdate: 9/10/2001 Birthplace: Religion: Roman Catholic Present Address: Lot 6 Block 25 Westville Homes Ligas 3 Bacoor Cavite Date of Admission: 2/28/2011 Informant: Reliability: CHIEF COMPLAINT: Jerky movement at right arm
Modified Developmental Checklist: Dental eruptions: Other behavioral problems (urinary continence; toilet training; tantrums):
retractions, clear breath sounds Heart and vascular system: Dynamic precordium, apex beat at 5th left ICS MCL, (+) Grade 3/6 holosystolic murmur paratesernal area, (+) heave parasternal area Abdomen: Flat abdomen, everted umbilicus, normoactive bowel sounds, o masses, no tenderness Extremities: Pulses full and equal, no edema, no cyanosis, (+) subcutaneous nodules on 1st, 2nd, 3rd, 5th PIPS right, and 2nd, 3rd PIPS left, and dorsal aspect of right pedis
NEUROLOGICAL EXAMINATION
Cerebrum: conscious, coherent, oriented to 3 spheres Cranial Nerves:
Pupils 2-3 mm ERTL, isocoric, (+) direct and consensual light reflex, (+) ROR, EOMS full and equal, can clench teeth, raise eyebrows, can smile, frown, (+) gag reflex, can turn head from side to side, tongue midline, (-) worming tongue
Cerebellar: can do FTNT and APST, (+) milkmaids grip Motor: 4/5 on right upper extremities, 5/5 on left upper extremities, and bilateral lower extremities Sensory: No deficits Reflex: ++ Meningeal signs: none
NEUROLOGICAL EXAMINATION
Epidemiology
Remains the most common form of acquired heart disease in all age groups worldwide Accounts for 50% of all cardiovascular disease and as much as 50% cardiac admissions in developing countries Incidence of both initial attacks and recurrences peaks 5-15 years old Philippine iIncidence is 0.9/1,000
Pathogenesis
Cytotoxic theory
Streptolysin O has direct cytotoxic effect on mammalian cells in tissue culture Inability to explain the latent period between Group A Streptococcus pharyngitis and the onset of acute rheumatic fever
Immune-mediated pathogenesis
Suggested by clinical similarity of acute rheumatic fever to other illness produced by immunopathogenic processes and by latent period between the Group A Streptococcus infection and acute rheumatic fever
Differential Diagnosis
SLE Juvenile Rheumatoid Arthritis Infective Endocarditis
Treatment
Complications
Long term sequalae are limited to the heart Increased risk for developing infective endocarditis
Prognosis
Depends on the clinical manifestations present at the time of the initial episode, severity of the initial episode, and the presence of recurrences ~70%of the patients with carditis during initial episode recover with no residual heart disease
Primary Prevention
Primary
antibiotic therapy instituted before the 9th day of symptoms of acute GAS pharyngitis
Secondary Prevention
Benzathine penicillin G (1.2 million units, or 600,000 units if 27 kg) delivered every 4 weeks.
Best antibiotic for secondary prophylaxis High risk: can be given every 3 weeks, or even every 2 weeks. Settings where good compliance with 4-weekly dosing can be achieved, more frequent dosing is rarely needed.
Secondary Prevention
ANCILLARY PROCEDURES
Blood Chemistry
ASO 592.86
Chest X-Ray
ECG
2D ECHO