GENITO-URINARY FISTULAS

Yashar Najiaghdam M.D

Definition

Abnormal communications between urinary & genital organs. Remember 2 golden rules

1st rule: urine may escape from

ureter tube, uterus, cervix, vagina bladder tube, uterus, cervix, vagina urethra always vaginal.
Part of the urinary tract is 1st to be described

2nd rule in naming a fistula,

Varieties
1. 2. 3. 4. 5. 6.

Vesico-vaginal Uretero-vaginal Urethro-vaginal Vesico-cervical Uretero-cervical Uretero-uterine

VESICOVAGINAL FISTULA (The Commonest)

Aetiology

Congenital: very rare. Traumatic fistula Obstetric trauma Necrotic obstetric fistula Traumatic obstetric fistula Surgical trauma Direct trauma Inflammatory disease Malignant neoplasms Radium necrosis

Necrotic Obstetric Fistula

Prolonged compression of soft tissues between head & brim of a narrow pelvis. ischaemia, pressure necrosis & sloughing of base of the bladder. Urethra is also often involved. Slough takes some days to separate Incontinence develops 5-7 days after labour Such fistulae are often surrounded by dense fibrosis

Traumatic Obstetric Fistula

Direct injury to bladder wall by sharp instrument (perforator or decapitation hook) during a difficult labour Forceps rarely cause it Incontinence Appears immediately After Labour

Traumatic Fistula

Surgical trauma: Bladder may be injured during vaginal operation as anterior colporrhaphy during abdominal operations as hysterectomy. Direct trauma: is a rare cause, but cases have occurred as a result of impalement.

Other Causes

Inflammatory disease: result from

Bilharziasis of bladder Tuberculosis of bladder. A pelvic abscess may open into bladder & vagina As advanced carcinoma of cervix or of bladder, or vagina By direct invasion of the wall and ulceration. Sloughing of the bladder As a complication of radium treatment used for cure of malignant disease in pelvis

Malignant neoplasms:

Radium necrosis:

Symptoms

Incontinence of urine

Complete (large fistula) OR Partial (small or high fistula)

DD: uretero-vaginal fistula.

Symptoms of vulvitis:

Pruritus, burning pain due to continuous discharge of urine. Due to ascending infection from vulva

Cystitis

Diagnosis

History of incontinence following labour or operation. Several days after labour necrotic obstetric fistula Immediately after difficult labour traumatic fistula. Palpation of anterior vaginal wall: Large fistula Can be felt Small fistulas cannot be felt, but surrounding fibrosis is usually palpable

Diagnosis

Inspection of the anterior vaginal wall

In Sims position or left lateral (semi-prone) position With the use of Sims speculum.

Diagnosis

For small and high fistula

Dye test: Injection of methylene blue into bladder by a catheter to outline the fistula while anterior vaginal wall is inspected by use of Sims speculum. DD: uretrovaginal fistula

Sometimes a metal catheter or sound is passed through the urethra to appear at the fistulous opening.

Management
Prophylaxis: Antenatal: Diagnosis of abnormalities that possibly result in fistula formation

contracted pelvis malpresentations

During labour Diagnose and deal with:

prolonged labour contracted pelvis Malpresentations high forceps forceps with incompletely dilated cervix risky destructive operations.

Risky operations should all be avoided

Management

If injury to the bladder is discovered during a difficult labour,

Dont suture the tear due to tissue oedema and friability. fix rubber catheter for 10 days The tear may heal completely or be much smaller

If the injury is detected some time after labour, as in cases of necrotic fistulas,

operations done except at least 3 months after delivery to allow for maximum involution of the tissues.

Preoperative Preparation

Treat vulvitis:

Cover skin of the vulva, and inner thighs by a thick layer of Vaseline, zinc oxide ointment or any bland ointment, to prevent maceration of the skin by the continuous discharge of urine.

Renal function tests: Culture of urine,

if pathogenic organisms are found, patient is given urinary antiseptics until urine is sterile.

Methylene blue test

to differentiate a small vesico-vaginal fistula from a uretero-vaginal fistula. 3 pieces of gauze are placed in the vagina 200 cc of sterile fluid coloured with methylene blue is Injected into the bladder The lowest piece of gauze is discarded as it is usually stained during filling the bladder. If the middle or upper pieces stain fistula is vesical If none of the pieces stain and the upper one is wet with uncoloured urine fistula is ureteric. If all are dry and unstained excludes vesical or ureteric fistula.

Methylene blue test

Cystoscopy

Determine relation of the fistula to ureteric openings in bladder Exclude multiple fistulas Reveal associated bladder pathology.

Chromocystoscopy IV Injection of 4 c.c. of 0.4% indigocarmine solution If kidney function is good Blue efflux from the ureter in 4 minutes.

Operation

flap-splitting operation, or dedoublement

Circular incision around the fistula. The 2 short longitudinal cuts upwards and downwards Through the thickness or the vagina but not the bladder. 2 flaps of vaginal wall. Free mobilization of the vaginal flaps from the bladder over a wide area, at least 1.5 cms around the fistula.

Long. incision

Circular incision Fistula

Operation

The hole in bladder is then closed by 2 layers of interrupted sutures going through muscle wall only & not piercing the mucous membrane. The vagina is then closed by interrupted sutures going through its whole thickness. A rubber catheter is fixed in the urethra Tight vaginal pack to prevent reactionary haemorrhage.

The saucerisation operation (Sims operation)

Indicated

If tissues are too adherent and fibrosed to do flap splitting After failure of the flap splitting. Edge of the fistula is excised removing a wider part of the vagina than of the muscle wall of the bladder Edges of both organs are simultaneously coapted together by the use of nonabsorbable sutures

Technique:

Certain high fistulae are better treated by abdominal (transperitoneal or transvesical) repair.

Postoperative Care

Recumbent position The bladder should be constantly empty. Fluids (3 litres/day). Urinary antiseptics & antibiotics. Vaginal pack is removed 24 hours after operation. Catheter is removed after 10 days. After its removal the patient is instructed to void urine every two hours by day & every four hours by night, to avoid over-distension of bladder & disruption of suture line.

Subsequent Management

Patient is instructed to

avoid sexual intercourse for 3 months avoid pregnancy for 1 year

Caesarean section is almost absolutely indicated.

URETERO-VAGINAL FISTULA

Cause:

Injury to ureter during a gynaecological operation as hysterectomy may develop following a difficult labour. Urine from affected ureter escapes from vagina while bladder fills up & empties normally from other ureter

It leads to incomplete incontinence

It is always small & high up in vagina lateral to cervix. Differentiated from a vesico-vaginal fistula by:

by methylene blue test. Cystoscopy shows ureteric efflux on one side only.

Prophylaxis

Ureteric injury can be avoided by

pre-operative intravenous pyelography ureteric catheterization proper surgical technique.

Treatment

Abdominal re-implantation of ureter into bladder. If not possible, ureter is transplanted into sigmoid colon. If kidney function is very poor on the affected side kidney can be sacrificed.

Kidney Function Tests

Blood urea: Normally 20-40 mg%. Specific gravity of urine before and after water administration (water concentration test): Normally high before, low after In chronic nephritis low fixed S.G. of about 1010. Urea concentration test: Normally urea in urine' should be 2% or over after administration of 15 grams of urea by mouth. Urea clearance test: It is a delicate test. It indicates the no. of cm3 of blood cleared of urea per minute Average = 70-120% < 50% renal impairment. Intravenous pyelography.

Types Of Incontinence Of Urine

1. 2. 3.

4. 5.

True incontinence genito-urinary fistula. Stress (Sphincter) incontinence weakness of Internal urethral sphincter. Urgency incontinence severe inflammation leading to marked irritation of bladder & so urge to pass urine cannot be inhibited & some urine will pass involuntary while patient is in her way to W.C. False incontinence retention with overflow Nocturnal enuresis.

Causes Of Retention Of Urine

Cause of urinary retention is an impacted pelvic mass. Diagnosis is made clear by attention to associated symptoms

Associated Conditions
Condition Primary amenorrhea Menorrhagia No menstrual upset Secondary amenorrhea Diagnosis Haematocolpos Retroverted gravid uterus Uterine fibroid

Ovarian or broad ligament tumour

Irregular bleeding

(1) threatened abortion from a retroverted gravid uterus,

(2) pelvic haematocele (3) pelvic abscess

Labour

Descent of the foetus to from a pelvic tumour