What is layout??

 Layout: the configuration of departments, work

centers, and equipment, with particular emphasis
on movement of work (customers or materials)
through the system

 Basic Purpose?

- To control cross contamination

The first phase :
• Which overall facility layout would best be able to handle
maximum projected demand for 10 years into the future?
• Determine the right type, quantity, and placement of
equipment for the long lead time equipment items that
are essentially integrated with the construction of the
facility.
Phase two :
• Identify the most effective staffing requirements and shift
patterns.
• Discover the reliability obtainable for the major
equipment cells.
• Determine the best material handling
 Feasibility

Macro process Review

Manufacturing Process

Personal Flow

Process Utility

Pharma Production Utility

Support area
1.Feasibility:
A]. Layout in terms of ROI.
B]. Under what regulation body plant have to work.
C]. Location approval.
D]. What hazardous material used in plant.

2. Macro process review

Review the project in macro level

3.Manufacturing process
A]. What type of manufacturing process involved
B]. What type of equipment used (new or existing)
C]. What space is required

4.Personal flow
A]. How many persons working in the area
B]. Efficient use of personnel
C]. Changing facility
D]. Lay out of equipment
5.Pharma production facility:
HVAC – QUALITY OF AIR
Water
Steam
Compressed air (clean air)
Electricity
Vacuum
Special gases
ETP

6.Support Area
Locker and change room, canteen, cafeteria , ware house

7.Flow of materials
a]. Perimeter Manufacturing

b]. Circular flow

c]. Straight line flow

- In this type of facility core area or central area is
ware house and manufacturing and packaging
area is on the peripheral area.

Advantage : Space conservation

Disadvantage : Contamination or mix ups .
Receiving of raw material , dispensing
,and
Ware house on one side and qurantine ,
manufacturing ,bulk stock & packaging
in central corridor .

Advantage :
Eliminate much of crossover trafic
 Advantage :-
Minimize contamination

 Disadvantage

Additional space required

 Quarantine
Capsule
Receiving Area Dispensing Weighing Washing and
Formation
Coating Rooms
QC Sampling coriidor
PACKAGING
And Tablet formation unit Tablet
Weighing Common corridor Coating
Change unit
Dry Syrup
room
Formation

Ware house

corridor
Shipping QA
room

Corridor

Canteen

FEMALE MALE
CHANGE CHANGE
Administration
ROOM ROOM
Production
Plant

Change
Staff Room Toilets
Staff
RAW MAT.
Wood free zone
RECEIPT PACK. MAT.
RECEIPT

DISPENSARY

PACK. MAT
STORE

MANUFACTURING

PRIMARY PACK
PRIMARY MAT. CLEAN DOWN
PACKING
GMP ZONE

SECONDARY
PACKING
DISPATCH
 Recieveing

Quaratine (first storage)

Final storage

Package component dispensing Raw material (Dispensing)

Granulation

Compression

Bulk Quarantine

Packaging Bulk stock

Shipping
Thank you !!