Beruflich Dokumente
Kultur Dokumente
Department of Physics & Applied Mathematics, PIEAS Nilore, Islamabad 45650, Pakistan
Introduction
Cancer is a term used for diseases in which abnormal cells divide without control and are able to invade other tissues. Cancer cells can spread to other parts of the body through the blood and lymph systems. There are more than 100 different types of cancer. Most cancers are named for the organ or type of cell in which they start. For example, cancer that begins in the colon is called colon cancer; cancer that begins in basal cells of the skin is called basal cell carcinoma.
Introduction (conti)
The main categories of cancer include: Carcinoma - cancer that begins in the skin or in tissues that line or cover internal organs. Sarcoma - cancer that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia - cancer that starts in blood-forming tissue such as the bone marrow and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and myeloma - cancers that begin in the cells of the immune system.
Origins of Cancer
All cancers begin in cells What happens when normal cells become cancer cells. The body is made up of many types of cells. These cells grow and divide in a controlled way to produce more cells as they are needed to keep the body healthy. When cells become old or damaged, they die and are replaced with new cells.
Symptoms of Cancer
Persistent Fatigue, Unintentional Weight Loss, Bowel Changes, Fever with pain Change in bowel habits or bladder functions Sores that do not heal Unusual bleeding or discharge Lumps or thickening of breast or other parts of the body Indigestion or difficulty swallowing Recent change in wart or mole Persistent coughing or hoarseness
Just four cancer sites lung, breast, colorectum and stomach are two-fifths (41%) of the worlds total cancer diagnoses in 2008
7.6
Asia Population Measures and Cancer Incidence and Mortality (Estimates Between 2005-2010)
Population Life Expectancy Number of New Cancer Cases* Number of Cancer Deaths*
2005-2010 estimates
2008 estimates
2008 estimates
% Under 15
% Over 60
Years
Total
% of World Total 48 29
Total
% of World Total 54 32
26% 19%
10% 14%
69 74
6,092,359 3,720,658
4,072,332 2,440,351
SouthCentral Asia
1,728,752
31%
7%
64
1,423,213
11
979,914
13
575,626
27%
9%
70
725,446
501,046
224,106
32%
7%
71
223,042
151,021
Breast
Data tend to support linearity
Lung
Common in Radon exposure
Bone
Bone surface short half life materials; 224Ra (T 1/2 3.6d) Bone volume long half life materials; 226Ra, 228Ra
Thyroid
Children in particular
Skin
X-rays
Cancer treatment
Local therapy:
Surgery. Radiation therapy.
Systemic treatment:
Chemotherapy. Hormonal therapy. Monoclonal antibodies.
Surgery
Surgery was the first modality used successfully in the treatment of cancer. It is the only curative therapy for many common solid tumors. The most important determinant of a successful surgical therapy are the absence of distant metastases and no local infiltration. Surgery may be used for palliation in patients for whom cure is not possible
Chemotherapy
Systemic chemotherapy is the main treatment available for disseminated malignant diseases. Progress in chemotherapy resulted in cure for several tumors. Chemotherapy usually require multiple cycles.
Radiation Therapy