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A protozoan which causes malaria along with Plasmodium vivax, Plasmodium malariae, and Plasmodium falciparum.

Its lifecycle is similar with the other plasmodium. It is the least among the four species to cause malaria. Responsible for benign malaria and can remain in the body for years without producing symptoms

Infected RBCs

Somewhat larger than normal, often with fringed or irregular edge, and oval in shape

Small trophozoite (early rings)


Growing trophozoite

Small, darker in color, and generally more solid than those of P. falciparum; Schffners dots present
Resembles closely same stage of P. malariae but is considerably larger; pigment is lighter and less cospicuous Seldom present About 25% of infected cells are oval shaped; usual picture is that of a round parasaite in the center of an oval cell; many cells with indefinite fringed outline; pigment lighter and less coarse than in P. malariae Usually 8 merozoites arranged around a central block of pigment Distinguished from P. malariae by size of infected cells and by Schffners dots

Large trophozoite Schizont (presegmenting)

Schizont (mature) Gametocyte

Fig. 1: Normal red blood cell; Figs. 2-5: Developing ringform trophozoites.

Figs 6-12: Developing trophozoites; Figs 13-15: Mature trophozoites.

Figs. 16-22: Developing schizonts. Fig. 23: Mature schizont.

Fig. 24: Macrogametocyte (female); Fig. 25: Microgametocyte (male).

Microgametocyte

Macrogametocyte

a parasitic disease which is spread from person to person by the bite of an infected Anopheles mosquito.

Malaria is a disease which affects 109 countries around the world. There are between 250 million and 500 million cases of malaria each year around the world. One million people die from malaria each yearmost of them children. The vast majority of malaria cases around the world occur in sub-Saharan Africa. 90% of all malaria deaths occur in sub-Saharan Africa. When insecticide-treated mosquito nets are used properly by three-quarters of the people in a community, malaria transmission is cut by 50%, child deaths are cut by 20%, and the mosquito population drops by as much as 90%. It is estimated that less than 5% of children in sub-Saharan Africa currently sleep under any type of insecticide-treated net.
http://english.prolasa.org/malaria-prevention/

Symptoms show take 8 14 days (P. ovale), but symptoms may occur after some months diarrhea fever loss of appetite rigors orthostatic hypotension headaches nausea sweating slight jaundice tiredness myalgia (limbs and back) cough enlarged liver and spleen abdominal pain (sometimes not palpable) vomiting

Many drugs have been used to treat malaria, however, resistance to these drugs have developed in the parasite and now it is standard practice to use at least two different drugs in the treatment of malaria. Quinine Chloroquine Amiodaquine Pyrimethamine Proguanil Sulphadoxine Mefloquine Doxycycline Clindamycin Lumafantrin Artemisinin and derivatives Atovaquone Primaquine Halofantrine

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