LECTURE PRESENTATIONS For CAMPBELL BIOLOGY, NINTH EDITION

Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson

Chapter 1

Introduction: Themes in the Study of Life

Lectures by Erin Barley Kathleen Fitzpatrick

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Overview: Inquiring About Life

An organisms adaptations to its environment are the result of evolution
For example, the ghost plant is adapted to conserving water; this helps it to survive in the crevices of rock walls

Evolution is the process of change that has transformed life on Earth

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Figure 1.1

Figure 1.2

 Biology is the scientific study of life Biologists ask questions such as

How does a single cell develop into an organism? How does the human mind work? How do living things interact in communities?

Life defies a simple, one-sentence definition Life is recognized by what living things do

Video: Seahorse Camouflage

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Figure 1.3

Order

Response to the environment

Evolutionary adaptation

Reproduction

Regulation

Energy processing Growth and development

Figure 1.3a

Evolutionary adaptation

Figure 1.3b

Response to the environment

Figure 1.3c

Reproduction

Figure 1.3d

Growth and development

Figure 1.3e

Energy processing

Figure 1.3f

Regulation

Figure 1.3g

Order

Concept 1.1: The themes of this book make connections across different areas of biology
Biology consists of more than memorizing factual details Themes help to organize biological information

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Theme: New Properties Emerge at Each Level in the Biological Hierarchy

Life can be studied at different levels, from molecules to the entire living planet The study of life can be divided into different levels of biological organization

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Figure 1.4

The biosphere Tissues Ecosystems Organs and organ systems

Communities Organelles Organisms

Cells

Atoms Molecules

Populations

Figure 1.4a

The biosphere

Figure 1.4b

Ecosystems

Figure 1.4c

Communities

Figure 1.4d

Populations

Figure 1.4e

Organisms

Figure 1.4f

Organs and organ systems

Figure 1.4g

50 m

Tissues

Figure 1.4h

Cell

10 m

Cells

Figure 1.4i

Chloroplast

1 m

Organelles

Figure 1.4j

Atoms

Chlorophyll molecule

Molecules

Emergent Properties
Emergent properties result from the arrangement and interaction of parts within a system Emergent properties characterize nonbiological entities as well
For example, a functioning bicycle emerges only when all of the necessary parts connect in the correct way

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The Power and Limitations of Reductionism

Reductionism is the reduction of complex systems to simpler components that are more manageable to study
For example, studying the molecular structure of DNA helps us to understand the chemical basis of inheritance

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 An understanding of biology balances reductionism with the study of emergent properties

For example, new understanding comes from studying the interactions of DNA with other molecules

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Systems Biology
A system is a combination of components that function together Systems biology constructs models for the dynamic behavior of whole biological systems The systems approach poses questions such as
How does a drug for blood pressure affect other organs? How does increasing CO2 alter the biosphere?

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Theme: Organisms Interact with Other Organisms and the Physical Environment
Every organism interacts with its environment, including nonliving factors and other organisms Both organisms and their environments are affected by the interactions between them
For example, a tree takes up water and minerals from the soil and carbon dioxide from the air; the tree releases oxygen to the air and roots help form soil

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Figure 1.5

Sunlight
Leaves absorb light energy from the sun. Leaves take in carbon dioxide from the air and release oxygen.

CO2

O2

Cycling of chemical nutrients Leaves fall to the ground and are decomposed by organisms that return minerals to the soil. Water and minerals in the soil are taken up by the tree through its roots.

Animals eat leaves and fruit from the tree.

Figure 1.5a

 Humans have modified our environment

For example, half the human-generated CO2 stays in the atmosphere and contributes to global warming

Global warming is a major aspect of global climate change It is important to understand the effects of global climate change on the Earth and its populations

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Theme: Life Requires Energy Transfer and Transformation

A fundamental characteristic of living organisms is their use of energy to carry out lifes activities Work, including moving, growing, and reproducing, requires a source of energy Living organisms transform energy from one form to another
For example, light energy is converted to chemical energy, then kinetic energy

Energy flows through an ecosystem, usually entering as light and exiting as heat
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Figure 1.6

Sunlight Producers absorb light energy and transform it into chemical energy.

Heat When energy is used to do work, some energy is converted to thermal energy, which is lost as heat.

Chemical energy

An animals muscle cells convert chemical energy from food to kinetic energy, the energy of motion. Chemical energy in food is transferred from plants to consumers.

A plants cells use chemical energy to do work such as growing new leaves.

(a) Energy flow from sunlight to producers to consumers

(b) Using energy to do work

Figure 1.6a

Sunlight

Producers absorb light energy and transform it into chemical energy.

Chemical energy

Chemical energy in food is transferred from plants to consumers.

(a) Energy flow from sunlight to producers to consumers

Figure 1.6b

Heat When energy is used to do work, some energy is converted to thermal energy, which is lost as heat.

An animals muscle cells convert chemical energy from food to kinetic energy, the energy of motion.

A plants cells use chemical energy to do work such as growing new leaves.

(b) Using energy to do work

Figure 1.6c

Figure 1.6d

Theme: Structure and Function Are Correlated at All Levels of Biological Organization
Structure and function of living organisms are closely related
For example, a leaf is thin and flat, maximizing the capture of light by chloroplasts For example, the structure of a birds wing is adapted to flight

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Figure 1.7

(a) Wings

(b) Wing bones

Figure 1.7a

(a) Wings

Figure 1.7b

(b) Wing bones

Figure 1.7c

Theme: The Cell Is an Organisms Basic Unit of Structure and Function

The cell is the lowest level of organization that can perform all activities required for life All cells
Are enclosed by a membrane Use DNA as their genetic information

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 A eukaryotic cell has membrane-enclosed organelles, the largest of which is usually the nucleus By comparison, a prokaryotic cell is simpler and usually smaller, and does not contain a nucleus or other membrane-enclosed organelles

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Figure 1.8

Prokaryotic cell Eukaryotic cell Membrane DNA (no nucleus) Membrane

Cytoplasm

Nucleus (membraneenclosed) Membraneenclosed organelles

DNA (throughout 1 m nucleus)

Figure 1.8a

Eukaryotic cell Membrane

Cytoplasm

Nucleus (membraneenclosed)

Membraneenclosed organelles

DNA (throughout 1 m nucleus)

Figure 1.8b

Prokaryotic cell DNA (no nucleus) Membrane

1 m

Theme: The Continuity of Life Is Based on Heritable Information in the Form of DNA
Chromosomes contain most of a cells genetic material in the form of DNA (deoxyribonucleic acid) DNA is the substance of genes Genes are the units of inheritance that transmit information from parents to offspring The ability of cells to divide is the basis of all reproduction, growth, and repair of multicellular organisms
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Figure 1.9

25 m

Figure 1.9a

Figure 1.9b

25 m

DNA Structure and Function

Each chromosome has one long DNA molecule with hundreds or thousands of genes Genes encode information for building proteins DNA is inherited by offspring from their parents DNA controls the development and maintenance of organisms

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Figure 1.10

Sperm cell

Nuclei containing DNA

Egg cell

Fertilized egg with DNA from both parents

Embryos cells with copies of inherited DNA Offspring with traits inherited from both parents

Figure 1.10a

 Each DNA molecule is made up of two long chains arranged in a double helix Each link of a chain is one of four kinds of chemical building blocks called nucleotides and nicknamed A, G, C, and T

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Figure 1.11

Nucleus DNA Nucleotide

C T
A Cell T A C C G T A G T

A
(a) DNA double helix (b) Single strand of DNA

Figure 1.11a

 Genes control protein production indirectly DNA is transcribed into RNA then translated into a protein Gene expression is the process of converting information from gene to cellular product

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Genomics: Large-Scale Analysis of DNA Sequences

An organisms genome is its entire set of genetic instructions The human genome and those of many other organisms have been sequenced using DNAsequencing machines Genomics is the study of sets of genes within and between species

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Figure 1.12

 The genomics approach depends on

High-throughput technology, which yields enormous amounts of data Bioinformatics, which is the use of computational tools to process a large volume of data Interdisciplinary research teams

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Theme: Feedback Mechanisms Regulate Biological Systems

Feedback mechanisms allow biological processes to self-regulate Negative feedback means that as more of a product accumulates, the process that creates it slows and less of the product is produced Positive feedback means that as more of a product accumulates, the process that creates it speeds up and more of the product is produced
Animation: Negative Feedback
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Animation: Positive Feedback

Figure 1.13
Negative feedback A
Enzyme 1

B D D D C
Enzyme 3 Enzyme 2

Excess D blocks a step.

D (a) Negative feedback W

Enzyme 4

Positive feedback

X
Enzyme 5

Excess Z stimulates a step.

Z Z Z

Y
Enzyme 6

Z (b) Positive feedback

Figure 1.13a

Negative feedback

A
Enzyme 1

B D D C
Enzyme 3 Enzyme 2

Excess D blocks a step. D

D
(a) Negative feedback

Figure 1.13b

W
Enzyme 4

Positive feedback

X
Enzyme 5

Excess Z stimulates a step.

Z Z
Z

Y
Enzyme 6

Z (b) Positive feedback

Evolution, the Overarching Theme of Biology

Evolution makes sense of everything we know about biology Organisms are modified descendants of common ancestors

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 Evolution explains patterns of unity and diversity in living organisms Similar traits among organisms are explained by descent from common ancestors Differences among organisms are explained by the accumulation of heritable changes

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Concept 1.2: The Core Theme: Evolution accounts for the unity and diversity of life
Nothing in biology makes sense except in the light of evolutionTheodosius Dobzhansky Evolution unifies biology at different scales of size throughout the history of life on Earth

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Classifying the Diversity of Life

Approximately 1.8 million species have been identified and named to date, and thousands more are identified each year Estimates of the total number of species that actually exist range from 10 million to over 100 million

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Grouping Species: The Basic Idea

Taxonomy is the branch of biology that names and classifies species into groups of increasing breadth Domains, followed by kingdoms, are the broadest units of classification

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Figure 1.14

Species Genus Family

Order

Class

Phylum Kingdom Domain

Ursus americanus (American black bear) Ursus

Ursidae

Carnivora

Mammalia

Chordata

Animalia

Eukarya

The Three Domains of Life

Organisms are divided into three domains Domain Bacteria and domain Archaea compose the prokaryotes Most prokaryotes are single-celled and microscopic

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Figure 1.15

(a) Domain Bacteria

(b) Domain Archaea

(c) Domain Eukarya

Kingdom Animalia

2 m

2 m 100 m Protists

Kingdom Plantae

Kingdom Fungi

Figure 1.15a

(a) Domain Bacteria

2 m

Figure 1.15b

(b) Domain Archaea

2 m

 Domain Eukarya includes all eukaryotic organisms Domain Eukarya includes three multicellular kingdoms
Plants, which produce their own food by photosynthesis Fungi, which absorb nutrients Animals, which ingest their food

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 Other eukaryotic organisms were formerly grouped into the Protist kingdom, though these are now often grouped into many separate groups

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Figure 1.15c

(c) Domain Eukarya Kingdom Animalia

100 m

Kingdom Plantae Protists

Kingdom Fungi

Figure 1.15ca

Kingdom Plantae

Figure 1.15cb

Kingdom Fungi

Figure 1.15cc

Kingdom Animalia

Figure 1.15cd

100 m

Protists

Unity in the Diversity of Life

A striking unity underlies the diversity of life; for example
DNA is the universal genetic language common to all organisms Unity is evident in many features of cell structure

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Figure 1.16

15 m

5 m

Cilia of Paramecium

Cilia of windpipe cells

0.1 m
Cross section of a cilium, as viewed with an electron microscope

Figure 1.16a

15 m

Cilia of Paramecium

Figure 1.16b

Figure 1.16c

0.1 m
Cross section of a cilium, as viewed with an electron microscope

Charles Darwin and the Theory of Natural Selection

Fossils and other evidence document the evolution of life on Earth over billions of years

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Figure 1.17

 Charles Darwin published On the Origin of Species by Means of Natural Selection in 1859 Darwin made two main points
Species showed evidence of descent with modification from common ancestors Natural selection is the mechanism behind descent with modification

Darwins theory explained the duality of unity and diversity

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Figure 1.18

Figure 1.19

Figure 1.19a

Figure 1.19b

Figure 1.19c

 Darwin observed that

Individuals in a population vary in their traits, many of which are heritable More offspring are produced than survive, and competition is inevitable Species generally suit their environment

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 Darwin inferred that

Individuals that are best suited to their environment are more likely to survive and reproduce Over time, more individuals in a population will have the advantageous traits

Evolution occurs as the unequal reproductive success of individuals

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 In other words, the environment selects for the propagation of beneficial traits Darwin called this process natural selection

Video: Soaring Hawk

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Figure 1.20

1 Population with varied inherited traits

2 Elimination of individuals with certain traits

3 Reproduction of survivors

4 Increasing frequency of traits that enhance survival and reproductive success

 Natural selection results in the adaptation of organisms to their environment

For example, bat wings are an example of adaptation

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Figure 1.21

The Tree of Life

Unity in diversity arises from descent with modification
For example, the forelimb of the bat, human, and horse and the whale flipper all share a common skeletal architecture

Fossils provide additional evidence of anatomical unity from descent with modification

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 Darwin proposed that natural selection could cause an ancestral species to give rise to two or more descendent species
For example, the finch species of the Galpagos Islands are descended from a common ancestor

Evolutionary relationships are often illustrated with treelike diagrams that show ancestors and their descendants

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Figure 1.22

Warbler finches

Insect-eaters

Green warbler finch Certhidea olivacea Gray warbler finch Certhidea fusca Sharp-beaked ground finch Geospiza difficilis Vegetarian finch Platyspiza crassirostris Mangrove finch Cactospiza heliobates

COMMON ANCESTOR

Seed-eater Insect-eaters

Bud-eater

Tree finches Ground finches

Woodpecker finch Cactospiza pallida Medium tree finch Camarhynchus pauper Large tree finch Camarhynchus psittacula Small tree finch Camarhynchus parvulus

Cactus-flowereaters

Large cactus ground finch Geospiza conirostris Cactus ground finch Geospiza scandens

Seed-eaters

Small ground finch Geospiza fuliginosa

Medium ground finch Geospiza fortis Large ground finch Geospiza magnirostris

Figure 1.22a

Warbler finches

Insect-eaters Seed-eater

Green warbler finch Certhidea olivacea

Gray warbler finch Certhidea fusca

Sharp-beaked ground finch Geospiza difficilis Vegetarian finch Platyspiza crassirostris

Bud-eater

Figure 1.22b

Mangrove finch Cactospiza heliobates Insect-eaters Tree finches Woodpecker finch Cactospiza pallida Medium tree finch Camarhynchus pauper Large tree finch Camarhynchus psittacula Small tree finch Camarhynchus parvulus

Figure 1.22c

Cactus-flowereaters

Large cactus ground finch Geospiza conirostris Cactus ground finch Geospiza scandens Small ground finch Geospiza fuliginosa Medium ground finch Geospiza fortis Large ground finch Geospiza magnirostris

Ground finches

Seed-eaters

Video: Albatross Courtship Ritual

Video: Blue-Footed Booby Courtship Ritual Video: Galpagos Islands Overview Video: Galpagos Marine Iguana Video: Galpagos Sea Lion Video: Galpagos Tortoise

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Concept 1.3: In studying nature, scientists make observations and then form and test hypotheses
The word science is derived from Latin and means to know Inquiry is the search for information and explanation The scientific process includes making observations, forming logical hypotheses, and testing them

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Making Observations
Biologists describe natural structures and processes This approach is based on observation and the analysis of data

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Types of Data
Data are recorded observations or items of information; these fall into two categories
Qualitative data, or descriptions rather than measurements
For example, Jane Goodalls observations of chimpanzee behavior

Quantitative data, or recorded measurements, which are sometimes organized into tables and graphs

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Figure 1.23

Figure 1.23a

Figure 1.23b

Inductive Reasoning
Inductive reasoning draws conclusions through the logical process of induction Repeating specific observations can lead to important generalizations
For example, the sun always rises in the east

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Forming and Testing Hypotheses

Observations and inductive reasoning can lead us to ask questions and propose hypothetical explanations called hypotheses

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The Role of Hypotheses in Inquiry

A hypothesis is a tentative answer to a wellframed question A scientific hypothesis leads to predictions that can be tested by observation or experimentation

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 For example,
Observation: Your flashlight doesnt work Question: Why doesnt your flashlight work? Hypothesis 1: The batteries are dead Hypothesis 2: The bulb is burnt out

Both these hypotheses are testable

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Figure 1.24

Observations

Question

Hypothesis #1: Dead batteries

Hypothesis #2: Burnt-out bulb

Prediction: Replacing batteries will fix problem

Prediction: Replacing bulb will fix problem

Test of prediction

Test of prediction

Test falsifies hypothesis

Test does not falsify hypothesis

Figure 1.24a

Observations

Question

Hypothesis #1: Dead batteries

Hypothesis #2: Burnt-out bulb

Figure 1.24b

Hypothesis #1: Dead batteries

Hypothesis #2: Burnt-out bulb

Prediction: Replacing batteries will fix problem

Prediction: Replacing bulb will fix problem

Test of prediction

Test of prediction

Test falsifies hypothesis

Test does not falsify hypothesis

Deductive Reasoning and Hypothesis Testing

Deductive reasoning uses general premises to make specific predictions For example, if organisms are made of cells (premise 1), and humans are organisms (premise 2), then humans are composed of cells (deductive prediction)

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 Hypothesis-based science often makes use of two or more alternative hypotheses Failure to falsify a hypothesis does not prove that hypothesis
For example, you replace your flashlight bulb, and it now works; this supports the hypothesis that your bulb was burnt out, but does not prove it (perhaps the first bulb was inserted incorrectly)

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Questions That Can and Cannot Be Addressed by Science

A hypothesis must be testable and falsifiable
For example, a hypothesis that ghosts fooled with the flashlight cannot be tested

Supernatural and religious explanations are outside the bounds of science

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The Flexibility of the Scientific Method

The scientific method is an idealized process of inquiry Hypothesis-based science is based on the textbook scientific method but rarely follows all the ordered steps

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A Case Study in Scientific Inquiry: Investigating Mimicry in Snake Populations

Many poisonous species are brightly colored, which warns potential predators Mimics are harmless species that closely resemble poisonous species Henry Bates hypothesized that this mimicry evolved in harmless species as an evolutionary adaptation that reduces their chances of being eaten

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 This hypothesis was tested with the venomous eastern coral snake and its mimic the nonvenomous scarlet kingsnake Both species live in the Carolinas, but the kingsnake is also found in regions without venomous coral snakes If predators inherit an avoidance of the coral snakes coloration, then the colorful kingsnake will be attacked less often in the regions where coral snakes are present
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Figure 1.25

Scarlet kingsnake (nonvenomous) Key Range of scarlet kingsnake only Overlapping ranges of scarlet kingsnake and eastern coral snake North Carolina South Carolina Eastern coral snake (venomous)

Scarlet kingsnake (nonvenomous)

Figure 1.25a

Scarlet kingsnake

Figure 1.25b

Eastern coral snake (venomous)

Field Experiments with Artificial Snakes

To test this mimicry hypothesis, researchers made hundreds of artificial snakes:
An experimental group resembling kingsnakes A control group resembling plain brown snakes

Equal numbers of both types were placed at field sites, including areas without poisonous coral snakes

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Figure 1.26

(a) Artificial kingsnake

(b) Brown artificial snake that has been attacked

Figure 1.26a

(a) Artificial kingsnake

Figure 1.26b

(b) Brown artificial snake that has been attacked

 After four weeks, the scientists retrieved the artificial snakes and counted bite or claw marks The data fit the predictions of the mimicry hypothesis: the ringed snakes were attacked less frequently in the geographic region where coral snakes were found

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Figure 1.27

RESULTS

100
Percent of total attacks on artificial snakes 83% 84%

Artificial kingsnakes Brown artificial snakes

80
60 40

20
0

17%

16%

Coral snakes Coral snakes absent present

Experimental Controls and Repeatability

A controlled experiment compares an experimental group (the artificial kingsnakes) with a control group (the artificial brown snakes) Ideally, only the variable of interest (the effect of coloration on the behavior of predators) differs between the control and experimental groups A controlled experiment means that control groups are used to cancel the effects of unwanted variables A controlled experiment does not mean that all unwanted variables are kept constant
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 In science, observations and experimental results must be repeatable

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Theories in Science
In the context of science, a theory is
Broader in scope than a hypothesis General, and can lead to new testable hypotheses Supported by a large body of evidence in comparison to a hypothesis

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Concept 1.4: Science benefits from a cooperative approach and diverse viewpoints
Most scientists work in teams, which often include graduate and undergraduate students Good communication is important in order to share results through seminars, publications, and websites

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Figure 1.28

Building on the Work of Others

Scientists check each others claims by performing similar experiments It is not unusual for different scientists to work on the same research question Scientists cooperate by sharing data about model organisms (e.g., the fruit fly Drosophila melanogaster)

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Science, Technology, and Society

The goal of science is to understand natural phenomena The goal of technology is to apply scientific knowledge for some specific purpose Science and technology are interdependent Biology is marked by discoveries, while technology is marked by inventions

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 The combination of science and technology has dramatic effects on society

For example, the discovery of DNA by James Watson and Francis Crick allowed for advances in DNA technology such as testing for hereditary diseases

Ethical issues can arise from new technology, but have as much to do with politics, economics, and cultural values as with science and technology

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Figure 1.29

The Value of Diverse Viewpoints in Science

Many important inventions have occurred where different cultures and ideas mix
For example, the printing press relied on innovations from China (paper and ink) and Europe (mass production in mills)

Science benefits from diverse views from different racial and ethnic groups, and from both women and men

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Figure 1.UN01

Figure 1.UN02

Cycling of chemical nutrients

Figure 1.UN03

Sunlight

Heat

Chemical energy

Figure 1.UN04

Figure 1.UN05

Figure 1.UN06

Figure 1.UN07

Figure 1.UN08

Figure 1.UN09

Population of organisms

Hereditary variations

Overproduction of offspring and competition Environmental factors

Differences in reproductive success of individuals

Evolution of adaptations in the population

Figure 1.UN10