Beruflich Dokumente
Kultur Dokumente
Drug Tolerance
Drug Tolerance
Mechanisms of Tolerance
Metabolic Tolerance
Mechanisms of Tolerance
Physiological Tolerance
Mechanisms of Tolerance
Mechanisms of Tolerance
Behavioral Tolerance
Classical Conditioning
The Terminology
The Terminology
Acquisition trials
Test trails
Extinction trials
It will dissipate
Typical Findings
Asymptote
CR strength
80
70
60
50
40
30
Line 1
Spontaneous Recovery
20
10
0
acq
acq
acq
acq
ext
training
ext
ext
ext
More phenomenon
Subject makes a CR to
stimuli similar in some way
to the CS
Only one CS has ever been %CR
directly paired with the US (it
is the CS+)
All others are CSStrength of CR is a function
of similarity to original CS+
Called Stimulus
Generalization
60
40
20
0
CS-
CS+
CS-
similarity to CS+
More phenomenon
80
70
60
50
40
% CR
30
20
10
0
CS-
CS+
CR
Bright light
Pupil constriction
food
Salivation
same
same
shock
Muscle contraction
same
Air puff
eyeblink
same
shock
Increase HR
Decrease HR
US = drug
UR = analgesia (reduced sensitivity to pain) or
euphoria
UR
OP
40
20
0
1
Operant Conditioning
B.F. Skinner
Emitted responses
Operant = interaction with the environment in order to obtain
reinforcement
Learning associated with operants is Type R learning
Operant Conditioning
B.F. Skinner
B.F. Skinner
Cumulative recording of
responses
Min
1
2
3
4
5
6
BP
2
3
7
3
0
0
CBP
2
5
12
15
15
15
16
14
12
10
cbp
bp
8
6
4
2
0
1
Classifying Reinforcers
Primary
Secondary
Classifying Reinforcers
Positive
Negative
Punishment
Omission Training
Addiction
Dependence