Modul PH

Coronary Heart Disease

Disusun oleh
GEO BERTHA FERNANDA
105070101111020

Task 1
A major tobacco company has 5000 workers. Most of the workers are
males (70%). The range of age of the workers is 20 56 years old. Based
on a survey in 2000, there were 500 workers with hypertension
(Hypertension criteria used: systolic pressure 160mmHg and diastolic
pressure: 90mmHg), 100 workers with diabetes mellitus type-2 and no
workers had history of coronary heart disease (CHD). The company
conducts periodic medical examination for their workers every year. Data
in 2010 shows that among 500 workers who had hypertension in 2000, 20
of them had history of CHD; meanwhile among those who had no
hypertension, 50 workers had experienced CHD. Furthermore, those with
DM type-2 in 2000, 10 of them had CHD and among those without DM
type-2, 60 workers were known experiencing CHD.
1. Based on the case above, is it true that hypertension is the dominant
risk factor of heart attack(use OR or RR calculation)? Why?
2. What is the prevalence of hypertension in the first survey (year
2000)?

1. Based on the case above, is it true that hypertension is

the dominant risk factor of heart attack(use OR or RR
calculation)? Why?
D+

D-

FR+

20

480

FR-

50

4450

RR HTN = A/ (A+B) : C/ ( C+D )

RR=20/500 : 50/4500
=1/25 :1/90
=3,6
D+

D-

FR+

10

90

FR-

60

4840

RR DM II=10/100 : 60/4900
=1/10 : 3/245
245/30=8,16

 Jadi dapat disimpulkan hipertensi

bukan merupakan faktor resiko yang
dominan dari CHD,namun faktor
resiko yang dominan adalah DM tipe 2
karena kemungkinan penderita
hipertensi mengalami CHD 3,6 kali
lebih besar dari pada orang yang tidak
mempunyai riwayat hipertensi. Nilai
ini lebih kecil dari faktor resiko lain
yaitu DM tipe 2 yang mempunya
resiko CHD 8,16 kali lebih besar dari
orang yg tdk punya riwayat DM

 2. What is the prevalence of

hypertension in the first survey (year
2000)?

persons having a particular disease during gv time p

prevalence
k
population during the same time period

Prevalence=500/5000 x 100% =10%

Task 2

 Please answer following questions using

data shown from the table above:
1. Please calculate the Odds Ratio for the
type of diet associated with CHD and
then explain your results briefly.
2. Please calculate the Odds Ratio for the
status for smoking and non smoking and
then explain your results briefly.
3. What can be concluded from the table?

D+

D-

FR+

111

95

FR-

89

105

A/(A+C) B/(B+D)
1.Ods ratio=
:
C/(A+C) D/(B+D)
= A/C:B/D=AD/BC
= 111.105/ 95.89
= 11655/ 8455
= 1,38
Jadi, orang dengan diet non-veg memiliki
resiko 1,38 kali lebih besar untuk mengalami
CHD dibandingkan orang dengan diet veg.

 2. Odds Ratio for the status for smoking

and non smoking = ad : bc
D+

D-

FR+

140

90

FR-

60

110

OR= 140.110 / 90.60

= 154/54
= 2,85
Jadi, orang yang merokok memiliki resiko
2,85 kali lebih besar untuk mengalami
CHD dibanding orang yang tidak merokok.

3. Smoking, alkohol dan diet non vegetable

merupakan faktor resiko dari CHD

Task 3

Please answer following questions: What can be concluded

from table 1 and 2 regarding hypertension problem in
Heilongjiang province?

 Pada tabel 1 didapatkan data laki-laki

mempunyai prevalensi yang lebih tinggi
untuk terkena HT,baik di rural dan urban
area (terutama urban area). Jadi dapat
disimpulkan laki-laki lebih beresiko
terkena HT
Tabel 2 dapat diamati terjadi kenaikan
prevalensi hipertensi sesuai dengan
kenaikan umur, jadi dapat disimpulan
bahwa umur merupakan salah satu faktor
resiko hipertensi