Beruflich Dokumente
Kultur Dokumente
GESTATIONAL
DIABETES
Evidence For Universal Screening
Laura Andersen & Danielle Major Galasso
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99 Topics - Objectives
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Background
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CDA Guidelines
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CDA Guidelines
Risk factors:
Previous GDM
Pre-diabetes
BMI > 30
Corticosteroid use
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CDA Guidelines
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CDA Guidelines
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Griffin, et al. 2000
Methods:
If 1 > more risk factor was present, women were allocated to risk-based
group and underwent a 100g OGTT at 32 weeks GA
Other women were allocated to the universal group who were screened
with a 1-hr 50g GCT at 26-28 weeks GA
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Griffin, et al. 2000
Methods cont:
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Griffin, et al. 2000
Results:
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Griffin, et al. 2000
Bottom line:
Validity:
Randomized
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HAPO group, 2008
Methods
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HAPO group, 2008
Methods contd
Outcomes
Glucose as
categorical
variable
and
primary
outcomes
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HAPO group, 2008
Results (contd)
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HAPO group, 2008
Validity
Randomized? N/A
Blinding?
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Crowther et al, 2005
Methods
Blinded
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Crowther et al, 2005
Methods (contd)
Interventions
Primary outcomes
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Crowther et al, 2005
Methods (contd)
Statistics
Intention to treat
Power calculation
(SF-36 = measure of
maternal health
status)
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Crowther et al, 2005
Validity
Randomized
Blinding
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Landon, et al. 2009
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Landon, et al. 2009
Methods:
Exclusion criteria:
preexisting diabetes
a history of stillbirth
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Landon, et al. 2009
Methods contd:
Statistical analysis:
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Landon, et al. 2009
Results:
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Landon, et al. 2009
Validity:
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Criteria for universal screening
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Summary
Questions
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References