Beruflich Dokumente
Kultur Dokumente
and Immunization
Prof Anura Weerasinghe
MD, FRCP(UK), DCH,
DTM&H(London), PhD(Japan)
Professor of Physiology
Faculty of Medicine
Ragama
Objectives
History of Immunization
Inoculation
Ancient times in India - Atharva Veda
A history of Medicine in Sri Lanka
by C. G. Uragoda
A centenary publication
Sri Lanka Medical Association
History of Immunization
1796 - First vaccination by Edward Jenner
1802 - First vaccination in Sri Lanka
1886 - compulsory vaccination
H. White, The Ceylon manual, 1908
1900 - Bacteriological Institute, Colombo
1967 - Last definitive case in Sri Lanka
1977 - Last endemic case in the world
- EPI/WHO
1991 - Hepatitis B and yellow fever
Artificial
Active
Passive
Infection
Utero
Neonatal
Active
Vaccines
Immunoglobulins Antisera
Normal(IM) Specific
Rabies
Hepatitis B
Tetanus
Anti-D
Immunological basis
of
Immunization
Immunization policy
Immune response
logistics
Epidemiology
Vaccine
Type of vaccine
mode of administration
Interval between doses
presence of other vaccines
Vaccine
Type of vaccine
mode of administration
Interval between doses
presence of other vaccines
Types of vaccines
Live attenuated
BCG, measles, OPV
Killed
Pertussis, Japanese encephalitis
Toxoids
Tetanus, Diphtheria
Genetically engineered
Hepatitis B
Expanded Programme of
Immunization; schedule in Sri Lanka
BCG - At birth
Hepatitis B 2,4 & 6 months
DPT & OPV - 2,4,6 & 18 months
DT & OPV - School entry
Measles - 9 months & 3 years (as MR)
aTD & Rubella - 10 to 15 years
Yellow fever
Travelers to Africa and South America
Non-EPI vaccines
Hib vaccine
MMR
Varicella
Typhoid
Cholera
Hepatitis A
Meningococcal
Pneumococcal
Rabies
DPT+Hib
DPT+Hep B
Hepatitis A & B
aTd
Objectives
Contraindications to DPT
Severe adverse event to DPT
anaphylaxis
collapse
encephalitis
non-febrile convulsion
Contraindications to live
vaccines
SCID
pregnancy
AIDS
Future vaccines
HIV
malaria
adult tuberculosis
cancer