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REIMAGINING GLOBAL HEALTH

ANDREW REED WELLE

Our world view reflects


our choice of information sources

http://www.who.int/tb/Global_TB_Facts.pdf

WHO Interim Policy Guidance on


Delamanid and Bedaquiline

Road maps for eliminating TB

http://www.who.int/tb/post2015_TBstr
http://www.stoptb.org/global
ategy.pdf
/plan/plan2/

Guides to MDR-TB Program management:


What is relevant and appropriate for my setting?

http://www.who.int/tb/publications
/pmdt_companionhandbook/en/

http://www.pih.org/library/pihguide-to-the-medicalmanagement-of-multidrugresistant-tuberculosis-2nd

http://www.pih.org/library/thesputnik-initiative-patient-centeredaccompaniment-for-tuberculosis-in-r

http://www.who.int/tb/pub
lications/global_report/en/

Scaling GeneXpert in the


Private Sector

75 GeneXpert
machines
Up to 450,000

TB REACH wave3: USD 3


million

Private providers and TB in Karachi

TB REACH Wave 3

Phone Based Screening and Incentives

Components of a Fully Integrated Digital


Radiology
& Computer Aided Detection for TB (CAD4T)
System

X-ray generator
Delft EasyDR System

Integrated detector Automated reading


Canon
CAD4TB

TB Electronic Recording and


Reporting

Integrating diagnostics
with care
Real-time connected diagnostics that reduce the time to
treatment to support a faster, more cost-effective health
system response

Faster Data Delivery


Improved Logistics
Scale

Integrating
Health Systems
Combining OpenMRS, OpenERP and
OpenELIS
to support healthcare providers in lowresource settings
PATIENT
REGISTRATION

INPATIENT
MANAGEMENT

CLINICAL SERVICES

FINANCIAL
OPERATIONS

LABORATORY

REPORTING

Thank you!

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Extra slides not part of presentation

How Tobacco control can benefit TB control


Exposure to TB
Non-Infection
(70-90%)

Infection
(10-30%)

Dormant TB(90%) well


never develop TBNOT infectious-

Active TB(10%) ill


develop TB within 2 years 5%develop TB many years later 5%-

Untreated
die within 50%
2 years
Sources: State Government of Victoria, Department of Health Services

38 |Brainstorm TB and Tobacco

Treated
Cured

More than 20% of global TB incidence


attributed to active smoking

PAF

P RR 1
P RR 1 1

Relative risk for


active TB disease

Weighted
prevalence
(22 HBCs)

Population
Attributable
Fraction

HIV infection

20.6/26.7*

1.1%

19%

Malnutrition

3.2**

16.5%

27%

Diabetes

3.1

3.4%

6%

Alcohol use (>40g


/ d)

2.9

7.9%

13%

Active smoking

2.6

18.2%

Indoor Air
Pollution

1.5

71.1%

23%
26%

Sources: Lnnroth K, Raviglione M. Global Epidemiology of Tuberculosis: Prospects for Control. Semin Respir Crit Care Med
2008; 29: 481-491.

39 |Brainstorm TB and Tobacco

TB Alliance New Drug


Pipeline

TAG Report- R&D Funding Investment

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