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Lymphatic
General
lymph?
Selected
Topics in Immunity
Lymphatic System
Absorbs
Returns
Additional
function in Immunity
Tissue
Lymphatic Vessels
Thymus
Bone Marrow
Spleen
Lymph
Lymph
absorbed by
the lymphatic
system
Lymphatic Tissue
Clusters of
Lymphocytes
and
macrophages
Lymphatic Tissue
Malt: (Mucosa Associated Lymphatic Tissue)
Diffuse array of lymphocytes found along body
nodules:
Lymphatic Vessels
Carry
and Transport
Lymph and proteins
Similar
Structure to veins
Tunica Interna: Thin
inner lining and valves
Tunica Media: Elastic
fibers and Smooth
Muscle
Tunica Externa: Thin
Outer Layer
Lymphatic Filters
Nodes- Screen and Filter
Lymph for infectious particles
Lymph
Spleen-
Subclavian
2 collecting Trunks
6 Lymphatic Trunks
More Collecting Vessels
Lymph Nodes
Collecting Vessels
Lymphatic Vessels
Lymphatic Movement
No
pump
Rhythmic
Skeletal
How
Muscles
is backflow prevented?
Thymus-
Makes T- Cells
Thymus
Break for
Dynamic Human
Inflammation
Non-specific
infection
4 signs of Inflammation
4 signs of Inflammation
Redness
Swelling
Heat
Pain
Whats the
purpose of pain?
Purpose of Inflammation
Remove
Invading Pathogens
Remove
Initiate
Tissue Repair
Mediators of Inflammation
Chemical
Messengers
Leukocyte
Chemical Messengers
Released
Bradykinin,
Stimulates Vasodilation
Increases Permeability of Capillaries
Whats Accomplished?
Chemical Messengers
Bradykinin,
Whats Accomplished?
Heats area causes redness and swelling
Dilutes toxins and helps Remove waste
Supplies oxygen and nutrients for tissue repair
Pain Response
Purpose?
Causes?
Pain Response
Purpose?
Causes?
Direct Nerve Damage
Pressure from Swelling
Chemical Stimulation particularly bradykinin
Leukocyte Deployment
Leukocyte:
Leukocytes
Why?
Leukocyte Deployment
Leukocytes
How?
1. Margination or pavementing: To
migrate to the wall of
a capillary
2. Diapedesis: Passage of blood cells
through vessel wall into tissue
3. Chemotaxis: Movement of a cell
towards or away a chemical source
more leukocytes
Phagocytosis
Leukocytes
Ejected
as Pus
Break for
Dynamic Human