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INFECTION
-
The
invasion
and
multiplication
of
microorganisms on the
tissues
of
the
host
resulting t signs and
symptoms as well as
immunologic response
. Microorganisms injures
the patient either by:
Competing with the hosts
metabolism.
Cellular damage produced by
the microbes
Intracellular multiplication.
PATTERNS OF A
DISEASE/INFECTION
SPORADIC DISEASESdiseases that occur
occasionally and irregularly
with no specific pattern.
EPIDEMIC DISEASESdiseases that occur in a greater
number than what is expected
in a specific area over a specific
time.
PANDEMIC DISEASES- an
epidemic that affects several
countries or continents.
ENDEMIC DISEASES- are
those that are present in a
population or community at
times. They usually involve few
people during specific periods.
A. CAUSATIVE
AGENT
Any microbe capable of producing a
disease.
It can be bacteria, spirochete, virus,
rickettsia, chlamydiae, fungi, parasite,
protozoa.
TERMS TO REMEMBER
PATHOGENECITY- ability to cause
disease.
VIRULENCE- ability to move through
the tissue.
INFECTIVE DOSE- number of
organisms to initiate infection.
B. RESERVOIR OF
INFECTION
C. THE PORTAL OF
EXIT
The path or way in which the
organisms leaves the reservoir.
Common portals of exit
Respiratory system
GUT
GIT
Skin and mucous membrane
placenta
Respiratory tract
Gastrointestinal tract
Genito-urinary tract
Open lesions
Mechanical escape
Blood
D. MODE OF
TRANSMISSION
Is the means by which the
infectious agent passes through
from the portal of exit of the
reservoir to the susceptible host
The earliest link to break the
chain of infection
2. AIRBORNE
TRANSMISSION
Occurs when fine microbial
particles or dust particles
containing microbes remain
suspended in the air for a
prolonged period.
3. VEHICLE
TRANSMISSION
The transmission of infectious
disease through articles or
substances that harbor the
organism until it is ingested or
inoculated into the host.
4. VECTOR- BORNE
TRANSMISSION
Occurs when intermediate
carriers such as fleas, flies and
mosquitoes transfer the
microbes to another living
organism.
E. PORTAL OF
ENTRY
The venue where the organism
gains entrance into the
susceptible host.
The infective microbes use the
same avenues when they exit
from the reservoir.
F. SUSCEPTIBLE
HOST
An immunosuppressed
individual; weakened host
Occurrence of infection
depends on the hosts..
Age, sex and constitution of the host
Nutritional status, fitness,
environmental factors
General condition, physical,
emotional and mental state
Absent of or abnormal
immunoglobulin
Underlying diseases
Treatment with certain antimicrobials,
corticosteroids, radiation r
immunosuppressive drugs.
EMERGING PROBLEMS IN
INFECTIOUS DISEASE
Increasing number of
organisms
Increasing numbers of
immunosuppressed
individuals
Persons with serious diseases
The use of indwelling lines
and implanted foreign bodies.
INFECTION
CONTROL
MEASURES
.. UNIVERSAL
PRECAUTION means that
all patients shall be
assumed infected with
HIV/ AIDS and other
blood borne pathogens.
LEVELS OF
PREVENTION
Primary prevention
Secondary prevention
Tertiary prevention
TYPES OF IMMUNITY
1. NATURAL
Passive- acquired through placental
transfer
2. ARTIFICIAL
Passive- acquired through the
administration of antitoxin,
antiserum, convalescent serum and
gamma globulins.
3. SUB-CLINICAL
-an immunity acquired through
constant exposure to a particular
disease or organism.
Suggested Control
Measures for Primary
Care Clinics
Masking
Hand washing
Gloving
Gowning
Eye protection
Environmental sanitation
ISOLATION
- Is the separation of patients
with communicable diseases
from others so as to prevent
or reduce transmission of
infectious agent directly or
indirectly
Purpose of Isolation
. To confine the infectious
agent to a circumscribed area
and to prevent the escape of
infection from that area.
STRICT ISOLATION
CONTACT ISOLATION
RESPIRATORY ISOLATION
TB ISOLATION
ENTERIC ISOLATION
DRAINAGE/ SECRETION PRECAUTION
UNIVERSAL PRECAUTION