MCQ

1) Bilirubin
A.Conjugated is a non-polar molecule
B.Conjugation is catalysed by gamma glutamyl transferase
C.Is formed in reticuloendothelial system
D.Is excessively synthesized during hemolysis
E.Is bound with globulin in the blood

1) Bilirubin
A.Conjugated is a non-polar molecule
B.Conjugation is catalysed by gamma glutamyl transferase
C.Is formed in reticuloendothelial system
D.Is excessively synthesized during hemolysis
E.Is bound with globulin in the blood
FFTTF

2) Hepatocellular failure

A.
B.
C.
D.
E.

increase ammonia
high blood urea
hypoglysemia
Hypoalbuminemia
Hyponatremia

2) Hepatocellular failure

A.
B.
C.
D.
E.

increase ammonia
high blood urea
hypoglysemia
Hypoalbuminemia
Hyponatremia

TFTTT

3) Biochemical changes that usually occur during acute hepatitis

A.
B.
C.
D.
E.

Hypoalbuminaemia
Raised plasma bilirubin
Normal plasma alkaline phosphatase
Positive urinary bilirubin
Increased plasma alanine aminotransferase

3) Biochemical changes that usually occur during acute hepatitis

A.
B.
C.
D.
E.

Hypoalbuminaemia
Raised plasma bilirubin
Normal plasma alkaline phosphatase
Positive urinary bilirubin
Increased plasma alanine aminotransferase

FTTTT

4) Jaundice
A.Associated with dark urine is due to unconjugated bilirubin
B.In association with pale stools suggests biliary obstruction
C.Is always detectable in patients with Gilberts syndrome
D.Is a sensitive indicator of the presence of liver disease
E.Is unlikely to be detectable clinically if the plasma bilirubin
concentration is < 50micromol/l

4) Jaundice
A.Associated with dark urine is due to unconjugated bilirubin
B.In association with pale stools suggests biliary obstruction
C.Is always detectable in patients with Gilberts syndrome
D.Is a sensitive indicator of the presence of liver disease
E.Is unlikely to be detectable clinically if the plasma bilirubin
concentration is < 50micromol/l
FTFFF

5) Acute viral hepatitis

A.AST & ALT raised to 10-200x
B.Mild increase GGT
C.LDH increased
D.ALP is increased more than AST
E.AST decline in parallel to bilirubin during recovery phase

5) Acute viral hepatitis

A.AST & ALT raised to 10-200x
B.Mild increase GGT
C.LDH increased
D.ALP is increased more than AST
E.AST decline in parallel to bilirubin during recovery phase
TTFFT

6) With reference of investigation of liver

A.Plasma albumin is normal in advanced cirrhosis
B.Plasma ALP markedly increased in acute hepatitis
C.Increase in plasma ALT activity indicate hepatocelular damage
D.Increase in plasma unconjugated bilirubin suggest billiary
obstruction
E.Plasma GGT activity is increased in patient using Rifampicin

6) With reference of investigation of liver

A.Plasma albumin is normal in advanced cirrhosis
B.Plasma ALP markedly increased in acute hepatitis
C.Increase in plasma ALT activity indicate hepatocelular damage
D.Increase in plasma unconjugated bilirubin suggest billiary
obstruction
E.Plasma GGT activity is increased in patient using Rifampicin
FFTFT

7) Regarding liver enzymes

A.gamma GT specific for alcohol liver diseases
B.ALT is microsomal enzymes
C.AST increased in necrotic liver cells
D.5-nucleotidase high in cholestasis
E.Liver is the sole site of albumin synthesis

7) Regarding liver enzymes

A.gamma GT specific for alcohol liver diseases
B.ALT is microsomal enzymes
C.AST increased in necrotic liver cells
D.5-nucleotidase high in cholestasis
E.Liver is the sole site of albumin synthesis
FFTTT

8) Conjugated hyperbilirubinaemia occurs in

A.hemolytic anaemia
B.criggler najar
C.gilbert syndrome
D.Dubin-Johnson syndrome
E.Rotor syndrome

8) Conjugated hyperbilirubinaemia occurs in

A.hemolytic anaemia
B.criggler najar
C.gilbert syndrome
D.Dubin-Johnson syndrome
E.Rotor syndrome
FFFTT

9) Biochemical changes in liver disease

A.ALP can be raised in oral contraceptive user
B.Increase ALP in prolonged biliary obstruction
C.Gamma globulin is increased in liver cirrhosis
D.Anti-mitochondrial antibody is found in more than 90% of patients
with primary biliary cirrhosis
E.Caeruloplasmin level is high in Wilsons disease

9) Biochemical changes in liver disease

A.ALP can be raised in oral contraceptive user
B.Increase ALP in prolonged biliary obstruction
C.Gamma globulin is increased in liver cirrhosis
D.Anti-mitochondrial antibody is found in more than 90% of patients
with primary biliary cirrhosis
E.Caeruloplasmin level is high in Wilsons disease
TTTTF

 10) Biochemical findings in prolong biliary obstruction include

increase of :
A. ALP
B. Urinary urobilinogen
C. Prothrombin time
D. GGT
E. Triglyceride

 10) Biochemical findings in prolong biliary obstruction include increase

of :
A. ALP
B. Urinary urobilinogen
C. Prothrombin time
D. GGT
E. Triglyceride
TFTTT