Histologi reproduksi pria

Afiana rohmani
BLOK 4 FK UNIMUS,
2013

http://www.uh.edu/~tgill2/image010.jpg

Male Reproduction System

ANATOMI , Consists of:
A pair of testes
A network of excretory ducts
epididymis
vas deferens
ejaculatory ducts
Seminal vesicles
Prostate
Urethra
Penis

Male Reproduction System

Functions
To produce, maintain and transport
sperm (the male reproductive cells) and
protective fluid (semen)
To produce and secrete male sex
hormones responsible for maintaining
the male reproductive system

TESTIS
Testes / testicles
(Gonads)
Produce sperm
(Spermatogenesis)
Sperm production
begins at puberty and
continues throughout
the life of a male

 Duct System
Epididymis
Sperm mature in
epididymis
Vas Deferens
Transports
mature sperm to
the urethra
Ejaculatory ducts
empty into the
urethra

 Seminal vesicles
Attached to vas
deferens
Produce a sugarrich fluid
(fructose) that
provides energy
to sperm

 Prostate Gland
Makes fluid

 Urethra
Tube that carries
urine from the
bladder to outside
of the body
Also carries
semen out of the
body

TESTIS

Diselimuti jar.ikat = tunika albuginea

Dibagi kompartemen2 =Lobulus testis
Tiap lobulus t.d Tubulus seminiferus
TS terpendam dalam jar.ikat longgar yang
t.d
pd , pl, saraf dan sel interstitial (Leydig).

 Tub seminiferus spermatogenesis

Sel Leydig hormon androgen testis.

Tubulus seminiferus
Tubulus brkelok-kelok, brawal dari saluran
buntu.
Muara lumen menyempit berlanjut ke
tubulus rektus rete testis duktuli
efferentes epididimis.

Tubulus seminiferus
Lapisan :
Jar.ikat fibrosa
Lamina basal td sel-sel mioid (sel
otot polos)
Epitel germinal
Sel epitel : td 2 jenis sel :
Sel sertoli = sel penyokong
Sel spermatogenik = td 4 lapisan
spermatogenesis spermatozoa.

spermatogenesis
development of sperm from spermatogonia
multiple division two times meiotic
1. Spermatogonia type A B
2. Primary Spermatocytes (44+XY), (>>)
3. Secondary Spermatocytes (22 +X) or(22+Y)
4. Spermatid
Spermiogenesis = maturation of spermatid into
sperm spermatozoa

Spermatogenesis
spermiogenesis

Sel sertoli
Sel penyokong
Menunjang, melindungi, mengatur nutrisi
spermatozoa yg sedang brkembang.
membentuk sawar testis-darah
Fagositosis
Msekresi protein ABP (Androgen Binding Protein) ,
(di bawah kendali testosteron &FSH). proses
spermatogenesis.

Jaringan interstitial testis

Merupakan jaringan ikat.
Kaya pd, pl, saraf . Mngandug sel Leydig
Sel Leydig = mhasilkan hormon testoteron.
stimulation of spermatogenesis, maintanance
of sex glands, sebaceous glands ...
regulated by luteinizing hormon (LH) of
hypophisis
Active in pubertation

Sperm maturity and transport

pathway

Tubuli recti
rete testis
intratestis
Ductuli efferentes
Epididymis
Ductus deferens
Ejaculatory duct

Tubuli recti et rete testis, tubuli

efferentes
Cuboideal cells and sertoli, surrounded by
lymphatic channels, blood vessels and
Leydig cells
no spermatogenic cells, only spermatozoa
cell

Epididymis
Ductuli efferentes ductuli epididimis
Ductuli epididymis Head :
columnar epitheluim with stereocilia and cilia
smooth muscle layer
Ductus epididymidis in body & tail
highly coiled one tubule - 4-6 m long
pseudostratified columnar epithel with stereocilia
two layers of smooth muscle thicker
function
Maturation, storage, transport

Ductus defernes (Vas deferens)

pseudostratified columnar epitel

lamina propria
3 layers of smooth muscle (L, C, L)
Ampula : thicker epithel
Muscular layer only at ampula

Seminal vesicles (Glandulae

vesiculosae)
folded mucosa with pseudostratified
epithel , with secretorius glands.
smooth muscle layer (C+L)
Activation regulated by testoteron.
function: 50-70% of seminal fluid
fructose

Prostate
30-50 tuboalveolar glands in fibromuscular stroma
tuboalveolar epitel silindris bertingkat.
3 regions of glands
Central zone
Transition zone BPH
Peripheral zone

Penis
three masses of erectil tissue
2x corpora cavernosa
1x corpus spongiosum (corpus cavernosa
urethra)
a. profunda a. nutritif & a.helicinae
communicating blood spaces (sinuses) surrounded
by connective tissue
artery -> sinus -> vein
dilatation of artery (NO) compress vein, sinuses fill
with blood -> erection occurs

urethra
1. Pars prostatika , ep transisional
2. Pars membranosa, ep silindris bertingkat sfingter
uretra eksterna
3. Pars bulosa
letak di korpus
4. Pars pendulosa
spongiosum (pars
cavernosa)
. Dilapisi epitel silindris bertingkat.
, Pars pendulosa = squamus
. Littre glands mucosa urethra

 TERIMA KASIH,
SEMOGA SUKSES