dr.

Harjono

SEMI SOLID PREPARATION, for application to the

skin with aspecific consistency- butter-like, homogenous and easy to smear without force
.(Plein&Plein28)

1. ACTIVE INGREDIENT Remedium cardinale

Remedium adjuvans

2. VEHICLE (VEHICULUM) OINTMENT BASE:

Vaselin-Petrolatum white/yellow
Adeps Lannae (wool fat); Lanolin
Polyethylene glycol, Prophylene glycol
Vegetable oil, hydrocarbons
Petrolatum are derived from crude petroleum.
Petrolatum is an amorphous compound of higher saturated hydrocarbon which temperature range 30-45 drt C
(S Jellinec113)

The kinds of ung. Epidermic;

Endodermic & mucous;
Diadermic;
Ophthalmic
Pastes
Cream Emulsion
Jelly Gel
Soap-Sapo
Emplastra,
Colemplastra

EPIDERMIC OINT., are intended to act solely on the surface of skin

to produce local effect

ENDODEMIC OINT; are intended to release medication that pegh

-trate into but not through the skin.
-partially absorbed and act as *emollient, *stimulan
*proliferants,*local irritants
DIADERMIC OINT; are intended to release medication that passes
through the skin and produse systemic effect.
OPHTHALMIC OINT; must be sterile preparation, according to
official standarts

Ung. 2 4

R/ Acid Salicylic
0. 200 --- 2%
Sulfur ppt
0. 400 ---- 4%
Vaselin
ad
10 g
m f l a ung

Ung Contra
Haemorrhoides 25 g

R/ Benzocain .0.050
Tannin .. 1.500
Adeps Lanae 20 %
Vaselin ad ..25 g
m f l a ung

Oculentum Terramycin 10 g R/ Terramycin . 0. 100

Adep Lanae ..
10 %
Ol. Sesami 2.5 %
Vaselin
ad 10 g
m f l a ung. Ophthalmicea

PASTES are stiff ointment-like preparation containing a

large quantity of such powder as Zinc oxide oe starch.
Pastes have drying action.
Pastes. R/ Sulfur ppt -- ----- -5
Zinc oxside ----- 5
Calc. Carbonate -5
Acid Boric ---------5
Vaseline -----------25
m f l a pastes
The advantage:* drying action- liquid adsorb
* protective
* difficult to smear
* difficult to removed
* oftently replacement

CREAM, are soft, semisolid or thick, liquid preparations

for application to the skin

.(Jenkins242)

O/W emulsion is preferred for internal use.

W/O emulsion usually designated as a lotion or cream is
generally used for external application.
The advantages: 1*unpleasent taste or noxious odor of the
oil is partially or completely disguised
2*the oil being in a finely dispersed state,
is more readily assimilated by the body.
3*W/O cream have greater emolient effect
and their therapeutic action is miller and more prolonged.
1. All purpose cream O/W

3. Cleansing cream W/O

2. Vanising cream O/W

4. Emulgide cream W/O

Cream o/w. All purpose cream.

R/ Paraffin Liq
16
Cera alba
3
Borax
o.200
Aquadest
9
m f l a cream
Jelly *are viscid, semisolid preparations usually made
by hydrating gums.
*It is of a consistency between that of thick,
viscous liquid and that of a fruit jelly.
*are pplied to the skin or mucous membrane
*lubricating effect
*as vehicle for active ingredients
Profenid jelly.--- Ketoprofen 2.5% gel.

SOAP- *are prepared by saponifying fat or oil with

alkalies.
*consistency depents on the predominating
acid and alkali used.(Davison322)
Soap- Sapo: S durus; (Soda soap) -detergentMedicinal soft Soap; Sapo molis (green soap-):
prepared from vegetable oil, oleic acid, glycerin
and potassium hydroxide.