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King Anthras Axe (B.

anthracis,
positive bacilli in
EF acts by
cereus)Large gramchains

increasing
intracellular cAMP

Fluoroquinolone
Tx
Tetracycline Tx

Widened mediastinum on
chest X-ray from pulm
infection
Poly-D-glutamate protein
capsule
EF = Edema
Wool sorters
factor
disease as spores
hide in wool
B. cereus

LF causes tissue
necrosis

Obligate
Aerobe

Map for MAP


kinase

Spore
forming
Vomiting/diarrhea
after eating
reheated rice

LF = Lethal factor

Black eschar
Pulmonary
hemorrhage

Rhesus Research Revolution (C.


Violet hues = Gram
tetani)

(+)
Tetanus toxin cleaves
SNARE
Thus, inhibiting
release of GABA
Toxoid vaccine
and glycine

Obligate
anaerobe

Retrograde
transport of the
toxin

Opisthotonus =
exaggerated arching
of the back

Tetanus toxin
blocks the action Spores in rusty
nails
of Renshaw cells
(G+G)
SNARE trap
Wrench and saw
for Renshaw

Spores in soil

Spore
forming

Risus sardonicus
= lock jaw or
evil grin

Robotulism (C. botulinum)


Gram positive
Transmitted by improper canning ACh is excitatory
of food
Descending
ACh releasing
flaccid
nerves targeted by
paralysis
botox
Toxin is protease
Ptosis and
that cleaves
diplopia
SNARES
Floppy baby
syndrome

Obligate
anaerobe

Nuts = spore
forming

Endospores
often found in
honey

FieldClean
Trip
to the Hershey Squirt Factory (C.
for clindamycin,
often a factor in difficile)
acquisition of C dif

IV metronidazole for Gram positive


Tx
rod
Exotoxin B

Exotoxin A
Brushing for
targeting the
brush border
(intestine)
Toxin detected in
stool

Exotoxin A causes watery


diarrhea

Oral vancomycin
for Tx
Pseudomembranous
Disrupts colitis
cytoskeleton by
depolymerizing
actin
Spore
forming

Private Ringens Motorcycle Accident (C.


Gram perfringens)
Clothes pins = lipid
bilayer
Alpha toxin (lecithinase) disrupts cell
membrane function
Causes
gas
gangrene
positive

Obligate
anaerobe

Treat with IV
G when
Double zone penicillin
of hemolysis
plated
Spores in soil

Also associated with motorcycle


accidents
May cause slow onset
Spore forming
diarrhea
Watery
Associated with diarrhea
deep penetrating
Alpha toxin is
wounds

Corazon de la Corrida (Corynebacterium


diphtheriae)
Plated on Loefflers
medium

Tellurite agar
Resp droplet
transmission

Gram positive, cat


+
Cardiotoxic
efects:
myocarditis,
arrhythmia, heart
block

Eleks test
Innactivated pertussis toxoid
vaccine
ADP Ribosylation of
EF-2

Bulls neck from


lymphadenopathy
Club shaped
rods in Y or X
formation

Metachromatic
granules

Pseudomembrane on throat and

Demyelination
starting in posterior
oropharynx

Santas List (Listeria monocytonegenes)


Gram positive,

Motile with flagella


at less than 30 deg
C

Beta
hemolytic

rod, facultative
anaerobe

Bacillus
Facultative intracellular
bacterium
Pregnant women
should not eat
soft cheese

And other dairy


products
Transmitted in
raw cheeses

Treat with ampicillin

Meningitis in neonates

Tumbling
motility

Actin rockets when in a

Catalase
positive

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