Antibiotik

Structure of a Bacterial Cell

Cell Wall
-maintains cell structure
-composed of peptidoglycan, a
polymer of sugars and amino acids
Flagella
-tail-like structure used for locomotion

http://en.wikipedia.org/wiki/Image:Average_prokaryote_cell-_en.svg

Plasma Membrane
-phospholipid bilayer surrounding cell
-contains proteins that play a role in
transport of ions, nutrients, and
wastes

Life Sciences-HHMI Outreach. Copyright 2008 President and Fellows of

Structure of a Bacterial Cell

Nucleoid
-region DNA is found in prokaryotes
DNA
-single double-stranded circular
chromosome
-no histone proteins
Plasmid
-small circular chromosome
-may carry an antibiotic resistance
gene

http://en.wikipedia.org/wiki/Image:Average_prokaryote_cell-_en.svg

Ribosomes
-site of protein synthesis (translation)

Life Sciences-HHMI Outreach. Copyright 2008 President and Fellows of

Antibiotics: Mechanisms of Action

Inhibition of Bacterial Protein Synthesis
- some antibiotics bind to the large or small subunit of the
bacterial ribosome
Examples: neomycin,
streptomycin,
azithromycin,
erythromycin,
tetracycline

ciences-HHMI Outreach. Copyright 2008 President and Fellowshttp://en.wikipedia.org/wiki/Image:Average_prokaryote_cell-_en.svg

of Harvard College.

Antibiotics: Mechanisms of Action

Inhibition of Bacterial Protein Synthesis
- some antibiotics bind to the large or small subunit of the
bacterial ribosome
Examples: neomycin,
streptomycin,
azithromycin,
erythromycin,
tetracycline

ciences-HHMI Outreach. Copyright 2008 President and Fellowshttp://en.wikipedia.org/wiki/Image:Average_prokaryote_cell-_en.svg

of Harvard College.