Magnetic Resonance

Imaging of the Rhesus

Monkey Brain
• Roland Tammer
• Sabine Hofer
• Klaus-Dietmar Merboldt
• Jens Frahm

ISBN: 978-3-525-40424-9
Website:
http://www.v-r.de/en/items/978-3-525-40424-9

All images are low resolution samples.

Magnetic Resonance
Imaging of the Rhesus
Monkey Brain
Magnetic resonance imaging (MRI) of the
central nervous system plays an
increasingly important role in the
neurosciences involving humans and
animals. Nonhuman primates are of special
relevance because of their immunological,
physiological, and behavioral similarities
to humans. Therefore, the lack of detailed
anatomical MRI data of the rhesus monkey
brain was a strong motivation for this
work. It provides the first comprehensive
in vivo MRI atlas of the living macaque
brain at the highest technical quality
currently available.
Three-dimensional coverage of the
brain in horizontal, coronal, and
sagittal sections at unprecedented
0.5 mm isotropic spatial resolution
is at the core of the atlas with an
indication of anatomical
structures. Multiple contrasts are
supplied compatible with human
MRI.
Advanced techniques such as
magnetic resonance angiography
and diffusion tensor imaging are
exploited for a visualization of the
intracranial vasculature and the
virtual reconstruction of nerve
fiber tracts, respectively.
“Readability” for the non-expert is
ensured by a simple introduction
into the principles and applications
of MRI. Detailed descriptions
cover all aspects of animal
handling, experimental procedures,
and image presentation in a
stereotaxic coordinate system.
The atlas is expected to serve as a
reference source for easy
identification of anatomical
structures in the rhesus monkey
brain. It is a “must” on the
desktop of primatologists and
neuroscientists in a broad range of
disciplines.
Table of Content

7 Preface
9 Introduction
11 Technical Aspects
11 Magnetic Resonance Imaging
12 Image Contrast
14 Experimental Details
15 Animals
16 Image Presentation
19 Anatomical MRI
20 Horizontal Sections
108 Coronal Sections
181 Sagittal Sections
208 Surface Reconstructions
220 Intracranial Vasculature
220 Magnetic Resonance Angiography
221 Experimental Details
222 Intracranial Arteries
226 Nerve Fiber Tracts
226 Diffusion Tensor Imaging
228 Fiber Tractography
229 Experimental Details
232 Major Nerve Fibers
244 Anatomical Variability
249 Abbreviations
250 References
252 Index
262 Authors
Jens Frahm Sabine Hofer

Klaus-Dietmar Jens Frahm

Merboldt
Roland Tammer

Roland Tammer, Ph.D., is Scientific

assistant at Biomedizinische NMR
Forschungs GmbH and DFG Center for
Molecular Physiology of the Brain,
Göttingen.

Vita
1996 Doctoral degree in veterinary medicine,
Justus-Liebig-Universität, Giessen,
Germany; 1994 Small animal veterinary
surgeon; 2000 Scientific assistant,
Deutsches Primatenzentrum GmbH,
Göttingen, Germany.

Main Focus
Magnetic resonance imaging studies of
laboratory animals.
Sabine Hofer

Sabine Hofer, Ph.D., is Scientific assistant

at Biomedizinische NMR Forschungs
GmbH and Bernstein Center for
Computational Neuroscience, Göttingen,
Germany.

Main Focus
Structural and functional aspects of the primate
central nervous system with the use of
functional magnetic resonance imaging,
diffusion tensor imaging, and fiber
tractography; comparative neuroanatomy of
human and nonhuman primates.
Klaus-Dietmar Merboldt

Klaus-Dietmar Merboldt, Ph.D., is senior

scientist at Biomedizinische NMR
Forschungs GmbH, Göttingen, Germany.

Vita
1984 Doctoral degree in physical chemistry,
Georg-August-Universität, Göttingen,
Germany; 1985 Scientific assistant, Max-
Planck-Institut für biophysikalische
Chemie, Göttingen, Germany.

Main Focus
Advanced methods for functional magnetic
resonance imaging of human brain
activation and diffusion tensor imaging of
nerve fibers.
Jens Frahm

Jens Frahm, Ph.D., is director of

Biomedizinische NMR Forschungs GmbH
(non-profit), Göttingen, Germany and
Professor for physical chemistry, Georg-
August-Universität, Göttingen.

Vita
1977 Doctoral degree in physical chemistry,
Georg-August-Universität, Göttingen,
Germany; 1982 Head of Biomedical NMR
research group, Max-Planck-Institut für
biophysikalische Chemie Göttingen,
Germany.

Main Focus
Development and application of magnetic
resonance imaging techniques for
noninvasive studies of animals and humans
with a special emphasis on the neurosciences.
• 263 Pages with many coloured
illustrations
• ca. 30,5 cm x 35,5 cm (12 inch x 14
inch)
• ISBN 978-3-525-40424-9
• Webpage at Vandenhoeck & Ruprecht
• Flickr Page with more pictures
• This presentation on Scribd
• This presentation on Slideshare