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synapse
Nervous system
neurons
The building blocks of
the nervous system
Neuron
STRUCTURE
axon:
axon
Has a specialized protein ion
channels that enable the axon to
conduct electrochemical signal from
the cell body to the axon terminal
That signal is also known as action
potential
Dendrites:
dendrites
Has specialized receptors that react
to the release of neurotransmitters
Molecules that produce a change in
polarization of the membrane
cells,
soma
The neuron contains the organelles
that are common to all cells:
cell membrane, nucleus, endoplasmic
reticulum, cytoplasm
body
Neuron
BASIC TYPES
Have process
extending
from each
end of the
cell body
Has a single
process
attached to a
around cell
body
Have many
dendrites
extending from
extending from
the cell body
and a single
axon
- the axon may split
into two or more collateral
axons after it leaves the
cell body
Multipolar neurons
Can be found in the :
anterior horn of the spinal cord (spinal
motor neurons)
Motor nuclei of cranial nerves
Central and autonomic nervous system
sites
Neurons
SOME REPRESENTATIVE NEURONS
Pyramidal cells:
Stellate cells:
Nervous tissue
TYPES OF STAINS
synapse
NERVOUS SYSTEM
ELEMENTS OF SYNAPSE
Chemical synapse consists of
TERMINAL BOUTON a swelling at
the end of axon terminal
Contains many synaptic vessels
ELEMENTS OF SYNAPSE
synaptic vessels contains
neurotransmitter molecules
PRESYNAPTIC MEMBRANE
POSTSYNAPTIC MEMBRANE
SYNAPTIC CLEFT spaces between the
two
ELEMENTS OF SYNAPSE
EXOCYTOSIS
RECEPTORS
SYNAPSE
IMPORTANCE OF SYNAPSE
SYMMETRIC or ASYMMETRIC
ASYMMETRIC SYNAPSES are characterized
by rounded vesicles in the presynaptic
cell, and a prominent post synaptic
density when observed under an electron
microscope. [usually EXCITATORY]
SYMMETRIC SYNAPSES on the other hand
have flatened or elongated vesicles ,
and do not contain a prominent
postsynaptic density. [usually INHIBITORY]
HYPERPOLARIZATION
vs.
DEPOLARIZATION
SYNAPTIC CLEFT
is a gap between
the pre- and
postsynaptic
cells that is
about 20nm
wide. The small
volume of the
cleft allows
neurotransmitter
concentration to
be raised and
lowered rapidly
PRESYNAPTIC
vs.
POSTSYNAPTIC
The presynaptic
neuron is the neuron
before the synapse, this
neuron is delivering the
"message" across the
synapse to the
postsynaptic neuron.
The postsynaptic
neuron is the "receiver"
of the neurotransmitter
"message"
PRESYNAPTIC
Contains the neurotransmitter,
mitochondria and other cell
bodies, called organelles
POSTSYNAPTIC
Contains receptor sites for
neurotransmitter