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Current concepts
Dr A D Deshpande
MD (Micro) , MD (Patho)
WHO
Int. Std. of TB
Care
Std. of TB Care
in India
RNTCP
India (25%)
India = 1500
deaths / day because
of Tuberculosis
Disea
se
60 days
Diagnos
is
New
Robert Koch
My name is
Koch
World TB day
March
24
March 24 1882 --
Dr Robert Koch discovered
TB bacillus
Lab Diagnosis
of Tuberculosis
Microbiology Tests
Sputum for ZN stain
Culture
PCR based Tests
LED
microscope
Fluorescent
microscope
Culture
LJ
Medium
BACTEC
MGIT
15 days
PCR Based
Tests
Gene Xpert
- Fast (90 mins)
- Easy to perform
- Genotypic Drug
Resistance (Rif)
- Dead Bacteria can
give Test positive
Extra pulmonary TB
Lymphnode Pus
CSF
Synovial fluid
Endometrial tissue
Pleural fluid
Any Pus
Serum
for TB
IgG , IgM
by Govt. of
India
7 June
2012
TB is a Notifiable
Disease
Dont send
patients
Blood to
Diagnose TB
Tuberculin Test
(Mantoux Test)
NOT RECOMMENDED IN
ADULTS
Latent TB
Child contacts
All Immunosuppressed HIV Patients
In US
Diagnosis of Tuberculosis in
Pathology
FNAC
Histopatholog
y
Thank you