Good luck for you

1
 Smooth muscle
Other type of muscle tissue different on skeletal and cardiac Called
.smooth also involuntary muscle
.It consists of narrow spindle shaped cells with a single
.Centrally located nucleus
.Unlike striated muscle
.Contracts slowly and automatically
It constitutes much of musculature of internal organs
. and the digestive system

2
Type of muscle tissue

3
 Muscle tissue
In this part you study only smooth

4
Muscle tissue
type of smooth muscle-
structure of smooth muscle -
-function of smooth muscle
contraction of smooth muscle-
smooth muscle summary-

5
type of smooth muscle

6
structure smooth muscle

7
 structure smooth muscle
Smooth muscle is made up of fusiform cells with
.a single nucleus
;The cells are arranged in sheets and contain three filament type
A)Actin filaments with no troponin and tropomyosin (5-8)
.times more actin than skeletal muscle
B)Long myosin filaments
C)Filaments of intermediate size which do not take
.Part in contraction

8
smooth muscle contraction

9
smooth muscle contraction
In smooth muscle although some calcium comes from
the sarcoplasmic reticulum; most come through opened calcium
channels in the plasma membrane and
Moves down its contraction gradient from the ECF
Smooth muscle cells have no need for an extensive sarcoplasmic
.reticulum or T-tubule system
.This calcium influx even in centre of the cell
In the case of smooth muscle the calcium binds to calmodulin (an
intracellular protein found in most
(. cells and structurally similar to troponin

10
 smooth muscle contraction
And this complex binds to and activates the protein
.Myosin kinase which then phosphorylate myosin
Phosphorylated myosin binds with actin so that cross
bridge cycling can begin (using energy from the breakdown
of ATP by myosin/ATP ase ; as there is no
Troponin- tropomyosin in smooth muscle; the increased
cytosolic calcium therefore acts as second
Messenger that initiates a chain of biochemical events
. That ends with the phosphorylation of myosin

11
 Function smooth muscle
The primary function of smooth muscle cells is to help
.hollow organs contract
These organs include (bladder and uterus)as well as
.Organs in the gastrointestinal tract
Smooth muscle cells also help the eyes maintain
. Normal focus

12
 Smooth muscle summary
. Nuclei- single , central
.Filaments scattered
.Control- automaticity, neural, hormonal
.Calcium source- ECF&SR
.Contraction- slower resists fatigue
. Energy source- mainly aerobic (some anaerobic)

13