1.

The following is/are TRUE of

mycobacteria
A. Slowly growing

B. Resistant to antibiotics

C. BOTH

D. NEITHER
2. The following drug/s is/are
BACTERICIDAL
A. ISONIAZID

B. RIFAMPIN

C. BOTH

D. NEITHER
3. The following are FIRST LINE DRUGS

A. ETHAMBUTOL

B. ETHIONAMIDE

C. BOTH

D. NEITHER
4. This/These drug/s provokes acute
gouty arthritis:
A. ETHAMBUTOL

B. PYRAZINAMIDE

C. BOTH

D. NEITHER
5. The ff. drug/s cause/s
Retro-bulbar neuritis
A. ETHIONAMIDE

B. PYRAZINAMIDE

C. BOTH

D. NEITHER
6. The ff. drug/s makes urine
orange in color
A. RIFABUTIN

B. RIFAMPIN

C. BOTH

D. NEITHER
7. The ff. drug/s is/are potent inducer
of cytochrome p450 enzyme
A. RIFAMPIN

B. RIFAPENTINE

C. BOTH

D. NEITHER
8. The ff. drug/s is/are used in conjunction with pyrazinamide in
short course (6mos.) regimens as a sterilizing agent against
residual intracellular organisms that may cause relapses:

A. RIFAMPIN

B. ISONIAZID

C. BOTH

D. NEITHER
9. The ff. DRUG/s has/have a half-life
of 8-11 hrs.
A. ETHAMBUTOL

B. PYRAZINAMIDE

C. BOTH

D. NEITHER
10. The toxicity of this drug can be readily
reversed by administration of pyridoxine.

A. PYRAZINAMIDE

B. ISONIAZID

C. BOTH

D. NEITHER
11. This/These DRUG/s crosses the BBB

A. STREPTOMYCIN

B. CAPREOMYCIN

C. BOTH

D. NEITHER
12. This/These DRUG/s can cause nephrotoxicity
and ototoxicity as adverse reactions:

A. STREPTOMYCIN

B. CAPREOMYCIN

C. BOTH

D. NEITHER
13. The ff. is/are the most serious
effect/s of cycloserine
A. PERIPHERAL NEUROPATHY

B. CNS DYSFUNCTION

C. BOTH

D. NEITHER
14. Resistance to this/these drug/s is due to the
single point mutations in the Gyrase A subunit:

A. FLUOROQUINOLONES

B. BEDAQUILINE

C. BOTH

D. NEITHER
15. This/These drugs must be
administered with meals and antacids:
A. CYCLOSERINE

B. AMINOSALICYLIC ACID

C. BOTH

D. NEITHER
16. The ff. adverse effects is/are
associated with Bedaquiline:
A. Cardiac Toxicity

B. Hepatotoxicity

C. BOTH

D. NEITHER
17. The ff. non-tuberculosis species of
mycobacteria is/are resistant to streptomycin:

A. Mycobacterium avium complex

B. Mycobacterium kansasii

C. BOTH

D. NEITHER
18. The ff. drug/s achieves therapeutic
concentrations with inflamed meningitis:

A. STREPTOMYCIN

B. RIFAMPIN

C. BOTH

D. NEITHER
19. This/These DRUG/s is/are metabolized chiefly
through the cytochrome P450 system:

A. BEDAQUILINE

B. FLOUROQUINOLONE

C. BOTH

D. NEITHER
20. The peak plasma concentration of this/these drug/s
increase approximately two folds when administered with
high fat.

A. CAPREOMYCINE

B. BEDAQUILINE

C. BOTH

D. NEITHER