Present by : 2007 kelompok 13 GI-Tract Colon Defecation Reflex Diagnose HIRSCHSPRUNG Causes Between the 5th and the 12th weeks of pregnancy, while the fetus is growing and developing, nerve cells form in the digestive tract, For unknown reasons, the nerve cells do not grow past a certain point in the intestine in babies with Hirschsprung's disease. Who is at Risk? 1 in 5000 newborns 4 boys for every 1 girl are affected. Children with Down syndrome have 50 times higher risk of having Hirschsprung's disease. There is possibly a genetic, or inherited, cause for Hirschsprung's disease. How to Diagnose Abdominal x-ray Barium enema Anorectal manometry Biopsy of the rectum or large intestine Treatment Surgery 2 steps : 1. Colostomy 2. Resection Duhamel Swenson Soave Complication Enterocolitis Perforation Peritonitis Sepsis Mal absorption