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Definition:
Infection due to plasmodium.
Aetiology
Plasmodium
Falciparum 90%
Vivax
Ovale
malariae
Epidemiology
Malaria attacks are very common in
infants and young children in endemic
area.
Attacks are rare below 3 months of age.
Peak is 6/12 -5yrs
Clinical features
Fever
General malaise
Fatigue
Sometimes diarrhoea and
vomiting
May become severe or
complicated.
Asymptomatic: older children that
have attained semi-immunity may
have asymptomatic malaria.
SEVERE AND COMPLICATED
MALARIA IN CHILDREN
1. CEREBRAL MALARIA
Mainly in children below 5 years of age.
Presents with:
Fever
Vomiting
Drowsiness
Convulsion
Unconsciousness (coma)
Artemether 20 coarterm
Lumefantrine 120 coartesian
ALU
Duo Cotecxin
Dihydroartemesinin 40
Piperaquine phosphate-320
Synestic combination
Active against asexual forms of
plasmodium, schizonts and
gametocytes.