Differences between

benign and malignant

tumour
Generally

Benign Malignant
Grows rapidly
Grows slowly Rarely encapsulated
Usually encapsulated Infiltrate surrounding tissue
Do not infiltrate other tissue Spread through lymph and blood
Do not spread Tend to recur after removal
Do not tend to recur Not resemble normal tissue, poorly differentiated
Cells resemble those normal tissue from which they arise Extensive tissue destruction
Minimal tissue destruction Typical cancer cachexia
Not produce typical cachexia Cause death
Usually not cause death
Radiologically

Non-aggressive lesion Aggressive lesion

Well demarcated Poorly demarcated

Narrow zone of transition Wide zone of transition
Absent or geographic osteolysis Poorly marginated osteolysis
Cortex may be displaced, remodelled and thin but not broken Cortex interrupted
Solid, smooth periosteal reaction Interrupted irregular periosteal reaction
+/- surrounding sclerosis No surrounding sclerosis
Static or slow rate of change Rapid rate of change
Management

Benign Malignant

Asymptomatic

-may never be needed If suspected malignant, patient is admitted for furher

-excise and curettage if bipsy indicated examination
Blood test , x-ray, ct and biopsy to confirm

Symptomatic Choice will be made after discussion with patient

-enlarging and painful even after end of bone growth Patient need to be confirm about pro and cons

-requires biopsy for confirmation Include amputation, limb sparring, different type of adjuvant

-local excision and curettage