References:

Brunton, P. A., Davies, R. P. W., Burke, J. L., Smith, A.,

No drill! Aggeli, A., Brookes, S. J., & Kirkham, J. (2013, August 23).
Treatment of early caries lesions using biomimetic self
assembling peptides - a clinical safety trial. British Dental Self-Assembling
No fill! Journal, 215(4), 6.
doi:http:/dx.doi.org.libproxy.lamar.edu/10.1038/sj.bdj.201
Peptide P11-4
3.741

No pain! Jablonski-Momeni, A., & Heinzel-Gutenbrunner, M. (2014,

May 15). Efficacy of the self assembling peptide P11-4 in
constructing a remineralization scaffold on artificially-
induced enamel lesions on smooth surfaces. Journal Of
Cost: Orofacial Orthopedics/Fortschritte Der Kieferorthopadie,
$300 for a box of 10 75(3), 175. doi:10.1007/s00056-014-0211-2

applicators good to Prakash, A., Parsons, S.J., Kyle, S., & McPherson, M. J.
(2012, July 3). Recombinant production of self-assembling
treat 10 teeth. structured peptides using SUMO as a fusion partner.
Microbial Cell Factories, 11(1), 92-101. doi:10.1186/1475-
2859-1192
Products:
Schmidlin, P., Zobrist, Katja., Attin, Thomas., Wegehaupt,
Repair, Protect, Dsenz Florian. (2015, November 2). In vitro re-hardening of
artificial enamel caries lesions using enamel matrix
proteins or self-assembling peptides. Journal of Applied
Oral Science Vol. 24 No. http://dx.doi.org/10.1590/1678-
77572015052

University of Leeds. (2011, August 23). Filling without Presented By:

drilling: Pain-free way of tackling dental decay reverses
acid damage and re-builds teeth. ScienceDaily. Retrieved Karissa Grado
October 25, 2016 from
www.sciencedaily.com/releases/2011/08/110823115402. Dental Hygiene Student
htm

http://clinicaltrials.gov/ct2/show/NCT02101255?term=pe
ptide+p11-4&rank=4 Morgan Fowler
http://credentis.com Regenerating Teeth: The New Dental Hygiene Student
dimension of Self-Assembling Peptides. (2017. Jan)
 How it Works
Self-assembling peptides are
peptides that undergo spontaneous
assembly to form nanostructures
and repair organic tissues. Peptide
P11-4 is a self-assembling peptide
that treats white spot lesions in a
non-invasive way that requires no
drilling on the tooth and is pain-free.
Similar to a sealant in the way it is
applied to the tooth, but works in a
different way and is 3x better. This
new regenerative technology is
painted on the surface of the
carious lesion and helps stop the
lesion from progressing any further.
P11-4 has been shown to start the
re-mineralization process of the
tooth, by producing hydroxyapatite
crystals that are essential in forming
enamel.
P11-4 Peptide matrix
Steps
1 Professional dental cleaning
2 Clean the affected tooth
surface with sodium
hydrochlorite 3% (20 sec)
3 Acid etching with phosphoric acid
gel 3537%. (30 sec)
Step 1: Perform professional
cleaning on teeth before
treatment of applying
Curodont.
Step 2: Clean and dry the
affected tooth surface with
sodium hydrochlorite 3% for
20 seconds.
Step 3: Apply acid etch of
37% phosphoric acid to the
tooth surface for 30 seconds
to roughen up enamel for the
peptide to adhere to the
lesion.
Step 4: Tooth is prepped and
ready for Curodont to be
painted onto the tooth
surface. Ensure moisture
control and let dry for 2
minutes until it is not visible.
Pictures from Day 1-Day 180