Presentors GROUP C-11

Bisht Anuj
Gupta Sharad
Singh Ankur
Rajput Vikas
- Manganese is a mineral element that is both
nutritionally essential and potentially toxic.

- Manganese is a micronutrient because it is

required in small quantities.
General Function
1) Manganese helps the body form connective tissue, bones, blood clotting
factors, and sex hormones.

2) It also plays a role in fat and carbohydrate metabolism, calcium absorption,

and blood sugar regulation.

3) Manganese is also necessary for normal brain and nerve function.

4) Manganese is a component of the antioxidant enzyme superoxide

dismutase (SOD), which helps fight free radicals.

5) Manganese overexposure is most frequently associated with manganism, a

rare neurological disorder associated with excessive manganese ingestion or
inhalation.
1) Free Radicals: Due to the antioxidant properties of manganese, the health
benefits of manganese include a special function of monitoring the activity of
free radicals in human body. These free radicals are capable of damaging
human cells and causing cancer and other devastating diseases, so adding
manganese supplements or food rich in this mineral is a very good choice,
particularly if you have other risk factors for various diseases.
2) Sugar level: Manganese has also exhibited efficiency in controlling the level of
sugar in human blood. This may further prevent the occurrence
of certain diseases like diabetes. To control the level of sugar in the blood,
manganese normalizes insulin synthesis and secretion, and the unpredictable
drops in blood sugar can be better regulated, providing a more normal and
functional life for diabetics.
3) Epilepsy: Low levels of manganese can act as a trigger for epileptic seizures.
Manganese supplements can aid in controlling the possibility of any minor or
major epileptic seizure. The exact mechanism for this is not fully understood,
but manganese has been shown to act as a vasodilator in various studies, and
there are some researchers who believe that this is the key to the anti-epileptic
quality.
4) Metabolism: Regulation of the bodys metabolism is one of the vital functions of
manganese. Manganese-activated enzymes help in the metabolism of
cholesterol, amino acids, and carbohydrates. It is also important for the
metabolism of Vitamins like Vitamin E and Vitamin B-1. Furthermore, it helps
the liver properly function and run smoothly, as well as being an essential part
of the metabolism of glutamine, the most abundant amino acid in the body, and
a key part of DNA polymerase.
5) Inflammation and Sprains: Manganese is a widely known remedy for sprains as
well as inflammation as it helps in increasing the level of superoxide
dismutase. This increased level is due to the antioxidant properties of the
mineral. Superoxide dismutase, also known as SOD, is normally found in very
low levels in patients with arthritis. SOD has anti-inflammatory qualities
which arthritis sufferers desperately need, so adding manganese back into the
body to increase synthesis and function of SOD has been connected with a
decrease in symptoms of this condition, according to various studies.
6) Preventing Osteoporosis: Manganese supplements are connected to the relief of
osteoporosis and osteoarthritis syndrome because it is an essential mineral
that has been proven to add to bone density and overall mineral density.
However, as an individual element in the creation and repair of bones, studies
are still somewhat lacking. In human testing, at least, most bone health
research is done with a complete panel of trace minerals, not just manganese.
Further studies have to be done on the specific roles and mechanisms of
manganese on the body.
7) Alleviating PMS syndrome: It is an unfortunate but unavoidable fact that many
women suffer from premenstrual syndrome (PMS). In these monthly situations,
manganese helps to alleviate the mood swings, headaches, depression and
irritability to a considerable extent. Studies have shown a connection between low
levels of various trace minerals, including manganese, in women who suffered from
particularly severe PMS symptoms, so supplementation is recommended. That being
said, the impact of manganese on the hormonal function of the body can be quite
noticeable, so speak with a doctor before using manganese supplementation to help
with PMS, since that is also heavily connected to hormones.
8) Aids in vitamin absorption: Manganese helps absorb vital vitamins like vitamin B and
E and minerals like magnesium. This is due to the role of manganese in the
enzymatic reactions that are required to absorb and utilize vitamins taken in
from food. Manganese is one of the most versatile co-factors for enzymatic
reactions, and if there is a risk of having a deficiency in certain vitamins, then be
sure to increase levels of manganese, as long as they are still within safe and non-
toxic levels.
9) Brain and nervous system: Manganese is essential for the healthy functioning of the
brain and it is also used to treat specific nervous disorders. This is most likely due
to the superoxide dismutase, which scavenges free radicals throughout the body,
including the neural pathways. Oxidation byproducts like free radicals are
everywhere in the body, and the brain can be negatively affected just as easily as
other parts of the body, therefore powerful antioxidants like SOD are required. Aside
from its antioxidant role, manganese can also bind with neurotransmitters and
stimulate faster or more efficient transmission of electrical impulses throughout the
body, in effect, speeding up cognitive function!
10) Glucose Metabolism: Manganese aids in regulating glucose metabolism in the
human body. This is one of the most important health benefits of manganese to
provide proper resources to different body parts, which increases energy and
functional efficiency. Also, when glucose is properly absorbed and utilized by
organ systems and muscles, there is less of a chance of excess buildup, which
is dangerous for patients with diabetics. Proper management of diabetes is
definitely aided by proper manganese levels in the body.
11) Digestive tract: Manganese is a mineral, which is helpful in maintaining the
functioning of the digestive track. This further improves the absorption of fat in
the process of digestion, and also reduces issues like constipation and bowel
discomfort. Manganese is also important in terms of efficient food utilization
and the transformation into usable energy.
DEFICIENCY SYMPTOMS MANGANESE:
Ataxia
Fainting
Hearing loss
Weak tendons and ligaments
Possible cause of diabetes. Medical studies indicate that
manganese deficiency impairs glucose metabolism and
reduced insulin production.
Manganese deficiency has been linked to myasthenia gravis.
Manganese activates several enzyme systems and supports
the utilization of vitamin C, E, choline, and other B-vitamins.
Inadequate choline utilization reduces the acetylcholine
synthesis, causing conditions such as myasthenia gravis (loss
of muscle strength).
 Infertility
Impaired glucose metabolism
Diseases of the skeletal structure, and impaired growth
Pancreatic dysfunction
Elevated blood pressure
Atherosclerosis
Reduced protein metabolism
Reduced immune function
Selenium deficiency
Depressed activity of mammary glands in nursing mothers
Mitochondrial abnormalities
 EXCESS SYMPTOMS OF MANGANESE
Psychiatric illnesses
Mental confusion
Impaired memory
Loss of appetite
Mask-like facial expression and monotonous voice
Spastic gait
Neurological problems