Beruflich Dokumente
Kultur Dokumente
Source: Adapted from Ghon and Kudlich, in Engel and Pirquet (eds.),
Handbuch de Kindertuberkulose, Georg Thieme Verlag, Stuttgart, 1930, Vol 1
Inhalation Alveoli Ingestion by PAMS
Destruction of PAMS
Calcification
Liquefaction
Manage
Class Contact Infetion Disease
ment
0 - - - -
I + - - proph I?
II + + - proph II?
III + + + therapy
Respirologi IKA FKUI - RSCM
Diagnosis
1. Tuberculin skin test
2. Chest X ray
3. Clinical manifestation
4. Microbiologic
5. Pathology
6. Hematological
7. Known infection source
8. others : serologic, lung function,
bronchoscopy
Respirologi IKA FKUI - RSCM
Tuberculin test
TB infection
cellular immunity
tuberculin reaction
Respirologi IKA FKUI - RSCM
TUBERCULIN
Tuberkulin PPD-S Tuberkulin OT
Strength
mg/dosis TU PPD RT 23 2 TU mg/dosis Pengenceran
1
First 0,00002 1 - 0,01
10,000
1
0,00001 5 2 -
2,000
Intermediate
1
- 10 5 0,1
1,000
1
Second 0,005 250 100 1,0
100
Respirologi IKA FKUI - RSCM Tuberculin
PPD S
Strength PPD RT23
Seibert
first 1 TU 1 TU
intermediate
5-10 TU 2-5 TU
(standard dose)
Pathology
Lymph node, hepar, pleura
On indication
Respirologi IKA FKUI - RSCM
Other examinations
Uji faal paru
Bronkoskopi
Bronkografi
Serologi
Complications of nodes
Complications of focus 1. Extension into bronchus
1. Effusion 2. Consolidation
Respirologi IKA FKUI - RSCM
2. Cavitation 3. Hyperinflation
3. Coin shadow
Resistance reduced :
infection 1. Early infection
(esp. in first year)
2. Malnutrition
3. Repeated infections :
measles, whooping cough 24 months
4-8 weeks 3-4 weeks fever of onset 12 months streptococcal infections
4. Steroid therapy
Development
Of Complex DIMINISHING RISK