dr. Susianti, M.Sc.

THE FUNCTIONS OF
CONNECTIVE TISSUE

 Providing and maintaining form in

the body
 Provide a matrix that connect and

binds the cells and organs

 Give support to the body
 DEVELOPMENT OF THE
CONNECTIVE TISSUE
Primitive
 Mesoderm  migrate Mesenchyme
from their site of origin,
surrounding and
penetrating developing
organs Mesenchyme
(Mesenchymal cells:
characterized by oval
nucleus with prominent
nucleoli and fine
chromatin)
 3 COMPONENTS OF
CONNECTIVE TISSUE

 Cells
 Fibers

 Ground Substance
 CELLS OF THE CONNECTIVE
TISSUE
 Fibroblast
 Fibrocyte
 Macrophage
 Mast Cells
 Plasma Cells
 Adipose Cells
 Leukocytes
8. Pigment cell

5. Small lymphocyte
4. Large lymphocyte

7. Eosinophil 9. Adipose cell

1. Macrophage 2. Fibroblast 6. Plasma cell
(histiocyte) 3. Fibrocyte
FIBERS OF CONNECTIVE
TISSUE:

 Collagen
 Reticular

 Elastic
 GROUND SUBSTANCE

 Consist of : - glycoproteins
- proteoglycans
 Colorless and transparant.
 Fills the space between cells and fibers.
TYPES OF CONNECTIVE TISSUE
LOOSE CONNECTIVE TISSUE
 Support many structures that are normally
under pressure and low friction.
 Consist of all the main component of
connective tissue proper.
 The most numerous cells are fibroblasts and
macrophages, but all the other types of
connective tissue cells are also present.
 Connective Tissue spread
1. Elastic fibers

2. Collagenous fiber
3. Adipose 8. Fibroblasts
cells
9. Collagenous fibers

4. Fixed macrophages 10. Elastic fibers

(histiocytes)

5. Eosinophils

11. Fixed
6. Lymphocytes macrophages

7. Mast cells
12. Capillary containing
erythrocytes

13. Cytoplasmic processes

14. Nucleus 16. Nucleus 18. Nucleus
15. Nucleolus 17. Vacuoles with 19. Mast cell granules
neutral red
I. Fibroblast II. Fixed macrophage III. Mast cell
DENSE CONNECTIVE TISSUE

 Consist of the same components found in loose

connective tissue, but there are fewer cells and
clear predominant of collagen fibers.
 Less flexible and far more resistant to stress
 There are dense irregular and regular
 Connective Tissue

1. Tendon cells
4. Nuclei of
tendon cells
(surface view)

2. Collagenous
fibers
4. Nuclei of
tendon cells
(slide view)

3. Bundle of
tendon fibers

Dense regular connective tissue

 Connective Tissue

7. Skeletal
muscle fibers
(t.s)
1. Bundles of
tendon fibers

2. Tendon cells 8. Interfascicular

(nuclei) connective
tissue
3. Connective
tissue between
bundles

4. Interfascicular
connective tissue
9. Tendon cells
5. Blood
vessels
6. Lamellar
(Pacinian 10.Collagenous
corpuscle) fibers

Dense regular connective tissue

 ELASTIC TISSUE
 Compound of band less thick, parallel elastic
fibers.
 Occurs infrequently
 Present in the yellow ligaments of the vertebral
collumn and in the suspensory ligament of the
penis.
 RETICULER TISSUE
 Consist of reticular fibers intimally associated
with specialized fibroblasts called reticular
cells.
 At the hematopoietic organs and lymphoid
organs.
 MUCOUS TISSUE

 Found mainly in the umbilical cord

= Wharton’s Jelly
 Has an abundance of ground substance
composed chiefly of hyaluronic acid. It’s jelly
like tissue containing very few fibers.
 Also found in the pulp of young teeth.