Beruflich Dokumente
Kultur Dokumente
Classified by cause
1. Decreased red cell production
a. Stem cell damage - neutrophils, platelets often
affected also
b. Defective red cell maturation
2. Increased red cell destruction (hemolysis)
a. Intrinsic defect in red cell leading to
shortened lifespan
b. External factors in blood or blood vessels
destroy red cells
3. Blood loss
HEMOLYTIC ANEMIA
“Sickled” cell
Leukemia
GUM INFILTRATION IN ACUTE LEUKEMIA
SKIN INFILTRATION IN ACUTE LEUKEMIA
CEREBRAL HEMORRHAGE
IN ACUTE LEUKEMIA
PURPURA IN LEUKEMIA
DISSEMINATED FUNGAL INFECTION
IN ACUTE LEUKEMIA
ACUTE LEUKEMIAS
Acute myelogenous leukemia (AML)
• adults > children
• fatal if untreated
• remission, occasional cure possible with intensive
chemotherapy
• sometimes curable with bone marrow transplant
Normal AML
Immature cells (blasts) in
Mature lymphocytes in
acute myelogenous
chronic lymphocytic leukemia
leukemia
CHRONIC LEUKEMIAS
Chronic myelogenous leukemia (CML)
• rare in children
• treatable but often fatal within 5-10 years
Newer treatments will probably improve the prognosis
• may be curable with bone marrow transplantation
“Reed-Sternberg” cell
characteristic of
Hodgkin’s disease
HODGKIN’S DISEASE
Staging