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• The scraping is viewed • Sarcoptes scabiei
under the microscope at
low magnification.
• The scabies mite
measures about 0.1 to
0.3 mm in diameter,
and
• is not visible with the
naked eye, but very
slight magnification will
make it visible.
Treatment of scabies
• Treatment of choice for • Some suggest that the
scabies is to apply Elimite should be
permethrin (Elimite)
overnight from the neck applied again overnight
down, and to ensure that to all persons five days
everyone in the patient's after the initial therapy
family is treated at the same to ensure that any adult
time. mites that are hatching
• The bedding and clothing from eggs that are not
from the past week should killed by the first
be washed or dry cleaned, or
it can be placed in plastic application can be
bags and set aside for a destroyed by the
week until any scabies mites second application.
within the bags die.
• Primary syphilis • Secondary syphilis
What is Syphilis?
• is a sexually transmitted disease (STD)
caused by the bacterium Treponema
pallidum. It has often been called “the
great imitator” because so many of the
signs and symptoms are
indistinguishable from those of other
diseases.
How do people get syphilis?
• Syphilis is passed from person to person
through direct contact with a syphilis sore.
Sores occur mainly on the external genitals,
vagina, anus, or in the rectum. Sores also can
occur on the lips and in the mouth.
Transmission of the organism occurs during
vaginal, anal, or oral sex. Pregnant women
with the disease can pass it to the babies
they are carrying. Syphilis cannot be spread
through contact with toilet seats, doorknobs,
swimming pools, hot tubs, bathtubs, shared
clothing, or eating utensils.
Primary Stage
• The primary stage of syphilis is usually
marked by the appearance of a single sore
(called a chancre), but there may be multiple
sores. The time between infection with
syphilis and the start of the first symptom can
range from 10 to 90 days (average 21 days).
The chancre is usually firm, round, small, and
painless. It appears at the spot where syphilis
entered the body. The chancre lasts 3 to 6
weeks, and it heals without treatment.
However, if adequate treatment is not
administered, the infection progresses to the
secondary stage.
Secondary Stage
• Skin rash and mucous membrane lesions characterize the
secondary stage. This stage typically starts with the
development of a rash on one or more areas of the body. The
rash usually does not cause itching. Rashes associated with
secondary syphilis can appear as the chancre is healing or
several weeks after the chancre has healed. The characteristic
rash of secondary syphilis may appear as rough, red, or reddish
brown spots both on the palms of the hands and the bottoms of
the feet. However, rashes with a different appearance may
occur on other parts of the body, sometimes resembling rashes
caused by other diseases. Sometimes rashes associated with
secondary syphilis are so faint that they are not noticed. In
addition to rashes, symptoms of secondary syphilis may include
fever, swollen lymph glands, sore throat, patchy hair loss,
headaches, weight loss, muscle aches, and fatigue. The signs
and symptoms of secondary syphilis will resolve with or without
treatment, but without treatment, the infection will progress to
the latent and late stages of disease.
Habits
• Copulation
• the male
• female, usually at night , burrows into
the skin, progressing at the rate of
about 2-3 mm per day.
• The female during her life span 0f 4-5
weeks deposits up to40-50 eggs, 2-4
at a time, in the burrow.
• The female may survive off the host
for 2-3 days at room temperature.
Life Cycle of Sarcoptes scabiei 8 to 15 days
Form
3 days a lateral branch
First nymph
male
Burrows
Into the
skin 2nd nymph
Female
2to3 mm
at night
Pathogenicity
• The preferential sites are the interdigital
spaces, the flexor surfaces of the wrist and
forarms, elbows, axillae, back, inguinal
region, and genitalia.
• The lesions appear as slightly reddish,
elevated tracts in the skin.
• Minute vesicular swelling , posibbly produce
by the iritating fecal deposits or excretions,
from beneath the gallery a short distance
behind the mite.
• The intense itching , aggragated by warmth
and precipitation , causes scratching, which
spreads the infestation, iritates the lesions,
and induces secondary bacterial infection.
• As a result multiple papular vesicular, and
pustular lesions may be produced.
• At first clinical manifestation may be mild, but
after some weeks the skins becomes
sensitized , resulting in an itching
erythematous eruption.
Diagnosis
• The type of lesion and an itching rash
are suggestive. Conclusive evidence is
obtained by removing the mite from its
burrow with a needle. The mites are not
always easy to find, since the number
of females, in spite of the high rate of
reproduction, in small.
• Prognosis is good with persistence
treatment
Scabies caused by Sarcoptes scabiei
Identification
• Identification requires that skin
scrapings be taken from the suspected
infested area and examined
microscopically.
• There has been much debate over
whether the scabies mite of man and
the scabies mites found in other
animals are one or several species.
• This is because mites from different
animals are morphologically
indistinguishable from S. scabiei.
Animal scabies
• The itch and mange mites of various domestic
animals (horses, pigs, dogs, cats, camels) can
infect humans.
• These mites are often morphologically in
distinguishable from human parasites and are
fully capable of penetrating human skin.
• The infection is usually self limited, however
because this mites do not form tunnels and
can not complete their life cycles.
• Nevertheless, human may react with severe
papular urticaria to these transitory infestations
Animal scabies
Treatment
• Infestation with the itch mites can be
eradicated by the use of 1% gamma benzene
hexachloride in a lotion BASE.
• The medicaton should be applied in the
evening after the lesions have been cleaned
and soften by soaking in a warm water and
should be left of overnight.
• One or two additional application, at weekly
intervals may be necessary to kill those mites
that hatch subsequent to the initial
treatment.
• For pediatric use, 10 per cent concentration ,
N-ethyl-o crotonotoluide (Eurax) in a cream
or lotion base, is prefered by many
physicians. It is applied to the skin of whole
body from the chin downs and a second
application is made after 24 hours
• A cleansing bath is given after another 24
hours.
• Allergic reactions and local irritation have
been reported.
Epidemiology
• Scabies is transmitted by personal
contact especially by person sleeping
together, less frequently by towels,
clothing and bed linens.
• Infectivity is low and the indication
tends to run a limited course in healthy
persons of cleanly habits
Control
• Prevention of scabies requires the
treatment of infected individuals, the
sterilizations of garments and bedding,
and personal cleanliness