Health talk

PROSTATE CANCER
BASHIRU AMINU
EPIDEMIOLOGY
 It is rare before 50 years, there is a steady
increase in its incidence afterwards
 14 % of males over 50 and 80% of those
over 70 years have the disease.
 there has been consistent increase in the
clinical incidence of the disease
worldwide and with ageing of the
population.
 Prostate cancer shortens life expectancy
dramatically in afflicted men.
 There are 2 types:
I. Latent histological form found in 30%
of men> 50 years and 60-80% of men >
80
2. Clinical form
ANATOMY/PHYSIOLOGY
ANATOMY/PHYSIOLOGY
RISK FACTORS
 Highly probable
-age
- family/genetic factors(1)hereditary
acluster of 3 or more in a nuclear family
(2)familial occurrence of the disease in
each of 3 generations in patients paternal
and maternal lineage (3) sporadic a
cluster of 2 relatives affected at 55yrs or
less
RISK FACTORS
-Race
-Cell behaviour
 Probable risk factors
-dietary fat
-cadmium-
smoking,batteries(alkaline),electric plating
-high vitamin A
-low vitamin D
-High risk sexual behaviour, multiple sexual
partners
-testosterone/DHT
PATHOLOGY
 histologically, 70-80% of prostate cancers
arise from the peripheral zone (PZ) which
is felt as the posterior part of the lateral
prostate on DRE.
 About 20% arise in the TZ and 10% in
the central zone (CZ).
 Spread by local, heamatogenous, lymphatic
spread.
CLINICAL FEATURES
 Asymptomatic disease
 Local disease with lower urinary tract
symptoms
 Locally invasive disease- In addition to above
+haemospermia, urinary tract obstruction,
haematuria, tenesmus, feacal fistula
 Metastatic disease-back pain, bone pain,
fractures, neurological symtoms
 Widespread metastasis-every where
 Incidental following prostaectomy
CLINICAL FEATURES
 History ,IPSS and complete physical
examination.
 DRE.
 PSA measurement TRUS (transrectal
ultrasound)-guided biopsy of the prostate
gland
 Digitally-guided transrectal Trucut biopsy.
 Histological grade
TREATMENT
 Confirm diagnoses
 Extent of the disease
 Treatment options
-watchful waiting
- CURE=radical prostatectomy
- PALLIATIVE=orchidectomy/
hormonal manipulation
Christian view
 Source of disease-luke 13:16 the woman bound by
satan 18yrs
 Aim of disease-Jn 10:10 to kill, destroy
 Why do they come-what selects a person Jer 31:29-
30
-what prepares the person Mt
13:25
-why some get healed/don’t mk
5:25
-differences in course of DX
 What is God`s mind set 1 peter 2:24
 Those with this mind set in the bible
Joshua, caleb, Enoch
Christian view
 Two days in a mans life Job 1:8
 Seek God first
 Them come to hospital-nothing wrong in
that
 Plead the blood over every test or
procedure
 Abundance in the heart takes time
 Place of meditation Joshua 1:8
 God still heals
THANK YOU FOR YOUR TIME