PATOLOGI SALURAN

NAFAS BAGIAN ATAS

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TUMOR RESPIRASI

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INVERTED PAPILLOMA

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INVERTED PAPILLOMA

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Inward epithelial tumor growth to stroma

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Tumor nest surrounded by inflammatory cells

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Proliferating columnar or squamous epithelial cells

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Mucin-containing cells with cillia

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6. KARSINOMA SEL
SKUAMOSA

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S C Carcinoma in situ
SCC in situ Bronchial washing

No gross mucosal abnormalities Bronchial brushing

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Early invasive SCC

SCC in situ with foci of early invasion (nodular Early invasive scc
thickening)

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SCC

Endobronchial SCC

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Well differentiated SCC

Keratin mass

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SCC moderately differentiated

Pearl formation

Central squamous differentiation

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SCC poorly differentiated

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7. SMALL CELL
CARCINOMA

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8. ADENOKARSINOMA

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Adenocarcinoma

This lobectomy specimen shows a lobulated, somewhat glistening mass

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Adenocarcinoma

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Adenocarcinoma
Cytology

3 dimension cell group, vacuolization

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9. BRONKOALVEOLER
KARSINOMA

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Bronchioloalveolar Carcinoma (BAC)
Non-mucinous type

Upper lobe is almost entirely consolidated by mucinous BAC, architecture is maintained,

and there is an absence of necrosis and hemorrhage

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Bronchioloalveolar Carcinoma (BAC)
Mucinous type

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Tumor projection to alveolar spaces

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Branching papillary formations

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Branching papillary formations

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Tall, columnar to cuboidal epithelial cells

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Bronchioloalveolar Carcinoma (BAC)
Non-mucinous type

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Bronchioloalveolar Carcinoma (BAC)
Mucinous type

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Bronchioloalveolar Carcinoma (BAC)
Mucinous type

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Bronchioloalveolar Carcinoma (BAC)
Mucinous type

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10. METASTATIC TUMORS
IN LUNG

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Pattern of Metastasis
Miliary & Lymphangitic Metastasis

-Numerous minute nodules and larger area of ill-defined consolidation

-Tthickening of the of small blood vessel, interlobular septa, and airways

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 Pattern of Metastasis
Multinodular metastasis

Yellow appearance to the metastatic nodules: Black appearance in some nodules: primary
abundant fat content of primary tumor: renal- Tumor is malignant melanoma
cell carcinoma

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Pattern of Metastasis
“Cannonball” metastasis

Primary tumor: osteogenic sarcoma. A variety of tumors: sarcoma, renal cell Ca,
malignant melanoma, colorectal Ca, may produce this appearance

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 Pattern of Metastasis
Lymphangitic metastasis

Primary tumor: leiomyosarcoma. Note the ar- Metastatic breast Ca. the perivascular lymphatics
borizing pattern produced by tumor within are markedly dilated and filled with clump of
Perivascular lymphatics tumor cells

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Pattern of Metastasis
Endobronchial metastasis

A nodular lesion protrudes into bronchial lumen

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Pattern of Metastasis
Endobronchial metastasis

A submucosal nodule of metastatic rhabdomyo- Microscopic involvement of the airway is far

sarcoma produces nodular protrusion of the More common than gross or clinically apparent
bronchial mucosa into the lumen involvement

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Pattern of Metastasis
Intra-arterial metastasis

The tumor embolus is coiled in worm-like Carcinomatous embolus in the lumen of small
fashion within the lumen of the artery artery

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Pattern of Metastasis
Pleural metastasis

Diffuse pleural metastasis simulating meso- Pleural metrastasis of adenocarcinoma

thelioma, the primary tumor is renal cell ca. mimicking mesothelioma
Solid ring of the tumor occupies the pleural
surface.

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Pattern of Metastasis
Interstitial metastasis

Interstitial metastasis of thymic carcinoid tumor Metastatic sarcomas more commonly adopt an
 nodular appearance. Interstitial pattern than epithelial tumors.

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Metastatic breast carcinoma

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Metastatic breast carcinoma

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Metastatic hepatoma

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Metastatic hepatoma

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11. MESOTELIOMA

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 TERIMAKASIH
TUHAN MEMBERKATI

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