Beruflich Dokumente
Kultur Dokumente
Jobin v joseph, False Localising Signs in Neurology, Indian Journal of Clinical Practice, Vol. 23, No. 9
February 2013
William Macewen.
Scottish neurosurgeon.
Headache, vomitting
Lesion?
LOCALISATION
• Supratentorial- 13 %
• Infratentorial- 4%
Tumours of the cerebellum rarely fail to
show the signs of cerebellar involvement.
• Paralyses of cranial nerves. 10 %
• Hemianopia.
• Jacksonian epilepsy.
• Bilateral spastic paresis.
• Cerebellar signs.
False localising signs.
Cranial nerve.
1) 6th nerve.
Most common
Seen in both supra and infra tentorial
lesions.
Reason: compression against the petrous
ligament or the ridge of the petrous
temporal bone.
2) Oculomotor nerve : Unilateral fixed dilated
pupil (Hutchinson’s pupil)
• Pseudoathetosis.
• Myasthenic nystagmus.
• Subcortical aphasia.
Collier’s Prime findings
• Signs appearing late in the course of intracranial
tumour, where general symptoms and signs
preexisted, are often of false portent.
• Absence of focal neurological deficits during the
early course of illness is in itself a most
important localizing indicator, confining the
disease to the supratentorial compartment.
• As the disease process progress, generalized
symptoms of increased intracranial pressure
may conceal once recognizable true localizing
signs.
• Tumours of the cerebellum rarely fail to show
the signs of cerebellar involvement
8 year child
Headache, vomitting
Lesion?
LOCALISATION
20 year old – headache, vomiting
7 months
Visual disturbance
10 months
left 6th CN palsy
2 months
Left ear complete deafness,
Left facial nerve palsy
3 months
Left cerebellar signs
• Glioma in left frontal lobe.
References
• James collier, The false localising signs of Intracranial tumour,
Neurology, 1904.