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Nucleotides and

Nucleic Acids

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• Nucleotides contain;
• Nitrogenious Base + Sugar + Phosphoryl group
Structure of nucleotides
Structure of nucleotides
Major purine bases of nucleic acids
Major pyrimidine bases of nucleic acids
Conformations of ribose
Conformations of ribose
Deoxyribonucleotides of nucleic acids
Ribonucleotides of nucleic acids
Nucleotide and nucleic acid nomenclature
Some minor purine and pyrimidine bases
Some minor purine and pyrimidine bases
Some adenosine monophosphates
Phosphodiester linkages in the covalent
backbone of DNA and RNA
Hydrolysis of RNA under alkaline conditions
Tautomeric forms of uracil
Schematic representation of nucleotide
sequence
Absorption spectra of common nucleotides
Hydrogen-bonding patterns in the base pairs
defined by Watson and Crick
The Avery-Macleod-McCarty experiment
The Hershey-Chase experiment
X-ray diffraction pattern of DNA
Watson-Crick model for the structure of DNA
Complementarity of strands in the DNA
double helix
Replication of DNA as suggested by
Watson and Crick
Structural variation in DNA
Comparison of A, B, and Z forms of DNA
Comparison of A, B, and Z forms of DNA
Palindromes and mirror repeats
Hairpins and cruciforms
DNA structures containing three of four
DNA strands- Hoogsteen pairing

Hoogsteen pairing
DNA structures containing three of four
DNA strands- Guanosine tetraplex
DNA structures containing three of four
DNA strands- H-DNA
Prokaryotic mRNA
Typical right-handed stacking pattern of
single-stranded RNA
Secondary structure of RNAs
Base-paired helical structures in an RNA
Three-dimensional structure in RNA
Reversible denaturation and annealing
(renaturation) of DNA
Heat denaturation of DNA
Partially denatured DNA
DNA hybridization
Some well-characterized nonenzymatic
reactions of nucleotides
Some well-characterized nonenzymatic
reactions of nucleotides
Formation of pyrimidine dimers induced by
UV light
Chemical agents that cause DNA damage
Chemical agents that cause DNA damage
Alkylating agents- dimethylsulfate
DNA sequencing by the Sanger method
DNA sequencing by the Sanger method
Strategy for automating DNA sequencing
reactions
Chemical synthesis of DNA
Nucleoside phosphates
The phosphate ester and phosphoanhydride
bonds of ATP
Some coenzymes containing adenosine
Some coenzymes containing adenosine
Some coenzymes containing adenosine
Three regulatory nucleotides