Beruflich Dokumente
Kultur Dokumente
GORDON WRIGHT
What you should learn from this LRGS
• 1. Outline the incidence and mortality of
common skin diseases
• 2. Describe the aetiology and pathogenesis of
common skin diseases
• 3. Describe the macroscopic and microscopic
features of common skin diseases
The problem for you
• What are common skin diseases?
ANATOMY OF THE SKIN
MORPHOLOGY MULTIPLE FUNCTIONS
• PROTECTION FROM THE
ENVIRONMENT
• PROTECTION OF
UNDERLYING ORGANS
• TEMPERATURE REGULATION
• OTHERS
PREVALENCE OF SKIN DISEASE
• Skin diseases are common, with 16% of
Australian general practice consultations
containing a dermatological element.
Recent Trends
• Fewer infections
• More neoplasms
• Overall about the same number of patients
presenting to general practitioners
• Thickened epidermis
• Intercellular oedema
• Oedema of papillary dermis
• Superficial inflammatory
infiltration
PROGNOSIS MAY BE DIFFICULT TO
DETERMINE
• Of the 571 children with reported or
examined eczema by the age of 7 years, the
proportion of children who were clear in
terms of examined eczema or reported
eczema in the last year at ages 11 and 16
years was 65% and 74%, respectively.
We shall present the remaining cases
linked to aetiology/pathogenesis
INFECTIONS OF THE SKIN
• VIRAL
• BACTERIAL
• FUNGAL
• PROTOZOAN
• METAZOAN
VIRAL INFECTIONS
• HUMAN PAPILLOMA VIRUS
• MOLLUSCUM CONTAGIOSUM
• HERPES SIMPLEX
• HIV
• Associated glomerulonephritis
IMPETIGO
CELLULITIS
DEFINITION
• Cellulitis is an acute, spreading pyogenic
inflammation of the dermis and subcutaneous
tissue, usually complicating a wound, ulcer, or
dermatosis. The area, usually on the leg, is
tender, warm, erythematous, and swollen. It lacks
sharp demarcation from uninvolved skin.
• Type
• Depth of invasion
• Lymphovascular invasion
• Perineural invasion
PROGNOSIS
• Around 97 out of every 100 men (97%) will
live for at a least year after they are diagnosed
with melanoma. Around 88 out of every 100
men (88%) will live for at least 5 years. And
around 86 out of every 100 men (86%)
diagnosed will live for at least 10 years.
Stage
Metastases
• Metastases in internal organs are sometimes removed,
depending on how many there are, where they are,
and how likely they are to cause symptoms. Metastases
that cause symptoms but cannot be removed may be
treated with radiation, immunotherapy, targeted
therapy, or chemotherapy.