EXTRA GENITAL

TRANSMISSIBLE VENEREAL
TUMOUR IN CANINE
BY : JAYSHREN GUNASEELAN

GUIDED BY : DR. SHIJU SIMON

Case no: 3643 2

Owner’s name: Kalaivanan

SIGNALMENT ANAMNESIS

Species : canine Owner reported that animal has been

involved in fighting and was bitten by
Breed : ND another stray dog.
Age : 9 years Lesion persisted for the past 10 days
Sex : male Anaimal has not been vaccinated or
dewormed
Colour : brown
Identification : Benny
Body weight : 11.5 kg
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GENERAL OBESERVATION
Animal has not been eating well (inappetance). Urine and faeces
was voided normally.

G/H - normal
B/H - active and alert
CMM - slightly pink and moist
TEMP - 39.1 C
L/N - palpable
STT - <2 sec
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OPHTHALMIC EXAMINATION

- Swelling/ mass noticed on the left eyes.

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OPHTHALMIC EXAMINATION

- Swelling/ mass noticed on the left eyes.

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TREATMENT ON THE DAY OF ARRIVAL

The eye was cleaned with normal saline and soft cotton bandaging
was done

• Inj - C-TAX - 120 mg I/M

Cefotaxime
Advised,

• Tab - Cefpet -100 mg x 6. nos

Cefpodoxime (1-0-1)

• Tab - Tramadol - 50 mg x 6. nos

(1-0-1)

• E-Collar
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TREATMENT ON 2ND DAY SINCE ARRIVAL

TEMPORARY TARSORAPHY
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DRUGS
PREMEDICATIONS

Inj- Atropine 0.5 ml- s/c

Inj- Xylazine 0.8 ml- i/m

ANAESTHETICS, ANALGESICS & ANTIBIOTICS

Inj- Ketamine + Xylazine 3.5 ml- i/v

Inj- Tramadol 1 ml- i/v

Inj- C-Tax 250 mg

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DIAGNOSTICS

IMMPRESSION BLOOD SAMPLE

SMEAR
HB : 5.5 BUN : 11.5
PCV : 17.1 CREA : 0.86
Suggestive for TVT. RBC : 2.80 TP : 7.0
WBC : 8300 ALB : 2.0
PLT :111000 CA : 9.3
. P : 3.61
BLOOD PARASITE: -
BLOOD PICTURE : POLYCHROMASIA
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CONFIRMATORY DIAGNOSIS

EXTRAGENITAL
TRANSMISSIBLE
VENEREAL TUMOUR
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TREATMENT ON THE 3RD VISIT

The area was Inj- vincristine 0.3mg Advised,

cleaned. Suture (strict i/v)
was removed. Syr – Ferrotoin x 1
Using a wet gauze Weekly once for the (5ml-0-5ml)
the eye was next 3 -4 weeks
cleaned with Syr – Liv 52 x1
normal saline (5ml-0-5m)
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2ND DOSE OF ANTI CANCER DRUG
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Use chartsGENITAL
EXTRA to explain TRANSMISSIBLE
your ideas
VENEREAL TUMOUR

• Transmissible venereal tumor (TVT) or Sticker tumor is a

naturally occurring horizontally transmitted round cell
tumor in domestic canids
White Gray Black
TRANSMISSIBLE
VENEREAL TUMOUR

EXTRA
GENITAL
GENITAL
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TRANSMISSION

Intact round cell  mucosal

membrane
White Gray Black
- Social behaviour
- Licking
- Sniffing
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OCCURENCE
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PREDISPOSING FACTORS

• Stress
• Immuno-compromised
• Age White Gray Black
• Climate
• Free roaming
• Sexually intact
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EXTRA GENITAL SITES

White Gray Black

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CLINICAL your ideas

• Abnormal growth of mass

• Cauliflower like in appearance
• Ulceration
• Pedunculated

OPHTHALMICWhite SIGNS Gray Black

• chemosis to episcleritis
• uveitis
• corneal edema,
• glaucoma
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METASTASIS PATHOPHYSIOLOGY
• Metastases occur in less than 5% of cases

Primary genital tumor

White Metastasis
Gray Black
hematogenous or lymphatic

subcutaneous pharynx tonsils spleen

tissue
liver kidneys eyes
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DIAGNOSIS

• History
• Impression smear
• Biopsy
• Physical examination
• X-RayWhite Gray Black

STAINS
- New methylene blue
- Harris Haematoxylin and Eosin
- Leishman Giemsa
- PAP stain
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CYTOLOGY

White Gray Black

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RADIOGRAPH

White Gray Black

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DIFFERENTIAL DIAGNOSIS
CYTOLOGY

White Gray Black

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CHEMOTHERAPY

Vincristine

- mitosis block
- microtublin
White
depolymerization
Gray Black
- strict i/v
- store at 2 -8 degree celcius
- dose : 0.025mg /kg/bwt
- 3-4 weeks – weekly once
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CHEMOTHERAPY

Doxorubicin
30mg/m2 i/v for every 21 days- 2 doses

Methotrexate
White Gray Black
2.5mg/m2 p/o
0.3-0.8 mg/ m2 i/v

Cyclophosphamide
200mg/m2 i/v
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OTHER THERAPIES

• Radiation therapy
• Cryotherapy
• Immunotherapy
• Surgery
White Gray Black
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