Vintamin B3

Vitamin B3 (Niacin) is used commonly to

refer to two different compounds, nicotinic
acid and niacinamide.
 Vintamin B3

•Niacin is one of the most stable of the B

vitamins. It is resistant to the effects of
heat, light, air, acid, and alkali.
•Niacin, is water-soluble, and absorbed
from the small intestine
• Small amounts may be stored in the liver
•Most of excess is excreted in the urine
Functions
 Involved in more than 50 different metabolic reactions in
the human body. Is required for cell respiration, helps in
the release of energy and metabolism of carbohydrates,
fats, and proteins
 Played the key role in glycolysis, are important in fatty
acid synthesis and in the deamination of amino acids.
 Precursor for coenzymes and help break down and utilize
proteins fats and carbohydrates.
 Stimulate circulation
 Reduce cholesterol levels in the blood
 Is important to healthy activity of the nervous system and
normal brain function, and a memory-enhancer.
 Supports the health of tissues of the skin, tongue and
digestive tract
 The synthesis of the sex hormones
 Helps synthesize DNA
Sources
 Only small to moderate amounts of Vitamin B3 occur in
foods
 Other Niacin is converted from the amino acid tryptophan
 The best Sources of Vitamin B3 are liver and other organ
meats, poultry ,fish and peanuts. All of which have both
niacin and tryptophan
 The richest sources of vitamin B3 are fish, tuna, salmon, and
halibut
 Yeast, dried beans and peas, wheat germ, whole grains,
avocados, dates, figs and prunes are pretty good sources of
niacin
 Milk and eggs are good because of their levels of tryptophan
 The milling and processing of whole grains can remove up
90% of the niacin
deficiency niacin
 Cause pellagra
 Niacin flush
 Can increase our blood homocysteine levels
 Characterized by bilateral 3 Ds (dermatitis,
diarrhea, and dementia)
 Toxicity
Shortage of niacin
 May be indicated with symptoms such as canker
sores, depression, diarrhea, dizziness, fatigue,
halitosis, headaches, indigestion, insomnia, limb
pains, loss of appetite, low blood sugar, muscular
weakness, skin eruptions, and inflammation.
Uses
 Pregnancy, lactation and grow periods need more B3
 Athletes requires more B3
 Stress, illness and tissue injure need more B3
 People eat a lot of sugar, refined and processed food
need more B3
 People consuming alcohol and not having enough protein
need more B3
 People with diabetes, glaucoma, any liver disease or
peptic ulcers need more B3
 Adult male need 16mg
 Adult female need 14mg
 Kids 4-8 years old need 8mg, Kids 9-13 years old need
12mg