Pharmaceutical Technology

Presentation
On
Types of containers and
Valve Assembly

Amity University, Noida

Amity Institute of Pharmacy

By : Unnati Garg
 1 2 TYPES OF
AEROSOL
Glass Metals
1) Uncoated Glass 1) Tin-plated Steel
CONTAINERS
2) Coated Glass 2) Aluminum
3) Stainless Steel
GLASS CONTAINERS

• These are preferred due to their aesthetic property and

absence of incompatibility.
• These are limited to products having lower pressure.
• These are used for topical and mdi aerosols.
• The uncoated glass containers are less costly and have high
clarity.
• The coated glass containers have a plastic coating which
prevents the glass from shattering.
 METAL CONTAINERS
• Tin-plated Steel containers: These consist of a sheet of
steel plate which is coated with tin by electrolytic process.
These are light weight and relatively inexpensive and are
generally used in topical aerosols.
• Aluminum Containers: These are mostly used in MDIs
and many topical aerosols. The material is light weight and
less reactive than other metals and have greater safety
against leakage, incompatibility and corrosion.
• Stainless steel Containers: Stainless steel is used when the
container must be chemically resistant to the product
concentrate. The main limitation of these containers is their
high cost.
 Maximum
Container Temperature
Pressure
Material (oF)
(psig) PRESSURE
Tin-plated steel 180 130
LIMITATIONS
Uncoated glass < 18 70
OF AEROSOL
Coated glass < 25 70 CONTAINERS
Aluminum 180 130

Stainless Steel 180 130

Plastic < 25 70
 VALVES

• A VALVE IS A DEVICE THAT REGULATES,

DIRECTS OR CONTROLS THE FLOW OF A
FLUID (GASES, LIQUIDS, FLUIDIZED
SOLIDS, OR SLURRIES) BY OPENING,
CLOSING, OR PARTIALLY OBSTRUCTING
VARIOUS PASSAGEWAYS.
 VALVE
ASSEMBLY
 Continuous Spray
Valve
TYPES OF
VALVES
Metering Valves
CONTINUOUS SPRAY VALVE

• These are mainly used for topical aerosols

• These consist of :
 Mounting Cap: Made from tin plated steel or brass
 Housing (Body): Made of Nylon or Derlin and
contains an opening at point of attachment of dip tube.
 Stem: Made from Nylon or Derlin
 Gasket: Made from Buna-N and neoprene rubber
 Spring: Made from stainless steel
 Dip tube: Made from polyethylene or polypropylene.
 METERING VALVES

• These are used for dispensing of potent

medication.
• These operate on the principle of a
chamber whose size determines the amount
of medication dispensed,
• Approximately 50 to 150mg ±10% of
liquid materials can be dispensed at a time
with the use of such valve.
•
 REFERENCES

• https://www.slideshare.net/revathireddypharma/aerosol-13798952
• http://www.threecell.com/client_archives/capco/technology.php?thepage=media
• https://pharmlabs.unc.edu/labs/aerosols/aerosolpackage.htm