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STEM Math & Chemistry

Connection to Medicine Project


NOAH MARTIN
CARTER PIKE
ASPIRIN

PRIMARY ACTIVE CHEMICAL: Acetylsalicylic Acid

FORMULA: C9H8O4

MOLAR MASS: 180 g/mol

ASSIGNED ELEMENT: Oxygen


TASK 4

If a prescription reads 1.5% w/v, how many grams of your


medication would be delivered by a 250 cc dosage?
1cc = 1mL
w/v = g/mL

250mL(1.5g/100mL) = 3.75g

ANSWER: 3.75g of Aspirin


Task 5

If a patient ingests 400 mg of medicine, how many atoms of your


specific element are they taking in?
As = Aspirin at = Atom molec = Molecule
O = Oxygen mol = Mole

400mgAs(1gAs/1000mgAs)(1molAs/180gAs)(6.022x10^23molecAs/1mo
lAs)(4atO/1molecAs) = 5.353E21atO

ANSWER: 5.353x 10^21 Atoms of Oxygen


Task 6

In order to obtain 15 grams of your particular element, what number of


molecules of your medicine must be ingested by the patient?
As = Aspirin at = Atom molec = Molecule
O = Oxygen mol = Mole

15gO(1molO/32gO)(6.022x10^23atO/1molO)(1molecAs/4atO) =
7.06x10^23molecAs

ANSWER: 7.06x10^23 Molecules of Aspirin


Task 7

Assuming your medicine can be delivered orally, how many cubic


centimeters of a 2:500 w/v solution are needed to prepare 13 Liters
of a 1:2000 w/v solution?

v(.004) = 13000mL(.0005)
V .004 = 6.5
V = 1625

ANSWER: 1625 cm^3


Task 8

Use Clark’s Rule to solve this situation. A 6 year old child weighs
42lbs. The adult dose of your medicine is 375 mg. What is the
appropriate dosage for the child?

(42lbs/150lbs) * 375mg = 105mg

ANSWER: 105mg
Task 9

If a patient takes 2-200 mg caplets, TID, how many days will it take for the
patient to ingest 4.75 moles of your medication?
As = Aspirin at = Atom molec = Molecule
O = Oxygen mol = Mole

200mg * 2 * 3 = 1200 mg/day

4.75molAs(180gAs/1molAs)(1000mgAs/1gAs) = 855000mg
855000/1200 = 712.5 days

ANSWER: 712.5 days


Task 10

If the half life of your particular medication is 8 days and you begin
with a 100 g sample, what mass remains after 40 days?

100g * (1/2) 40/8 = 3.125g

ANSWER: 3.125g

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