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Epidemicity
• In 2012, about 900,000 people lost their lives to TB, according to WHO estimates. The
majority of TB-related deaths happen in poorer countries. It is one of the top causes of
death for people who have HIV
• India accounts highest TB burden in world , accounts for 20% of global burden .
• Two out of every five Indians are effected with TB disease .
Mode of transmission
• Mainly transmitted by droplet
infection generated by sputum
positive patients with pulmonary
TB.
• Coughing and sneezing generates
largest no of droplets of all sizes
which are fresh enough to carry a
viable organism .
• Incubation period –
3-6 weeks from the day of receiving
the organism .
Control of the disease
1)RNTCP (Revised National Tuberculosis Control Program )
• The govt of india , WHO and world bank together reviewed the NTP(1962) in 1992.
• The main pillars of revised strategy are – 1) achievement of not less than 85% of cure
rate among infective cases, 2) detecting 70% of estimated cases through quality sputum
microscopy, 3) involvement of NGO, 4) DOTS (DIRECT OBSERVED THERAPY SHORT ) .
2) BCG vaccination
• The aim is to induce a benign , artificial primary infection which will stimulate an
acquired resistance to possible subsequent infection with virulent tuberculi bacilli .
• The vaccination is given soon after birth with in 4weeks a dose of 0.05ml intradermally .
AIDS / HIV
• AIDS- Acquired immune deficiency syndrome
• HIV- Human Immuno-Deficiency virus .
• In this condition the virus breaks down the body’s immune system ,
leaving the victim vulnerable to life threatening opportunistic
infections , neurological disorders or unusual malignancies .
• AIDS refers to the last stage of HIV infection
Incubation period –
Few months to 10 years or even more