SEMINAR ON

ROLE OF PHARMACIST IN MANAGEMENT OF ADR

PRESENTED BY,
IMRAN SUFAIR.M
Reg.no:15Q3407

4th pharmD(2018-19)

Department Of Pharmacy Practice

Mallige College Of Pharmacy, B’lore-90
 Management of ADR

• successful management of adverse drug reaction requires early identification

and prompt treatment of anaphylaxis, whether due to immunoglobulin(Ig) E-or

non - IgE mediated mechanisms of mast cell mediator release.

• Acute therapy is directed towards enhancement of oxygenation and

maintenance of normotension.

• Although the offending drug is discontinued, a necessary drug of which there

is no satisfactory alternative occasionally may be continued without danger of

further anaphylaxis.
IMRAN SUFAIR.M
• Emergency measures may be needed to maintain the airway.

• a good management also requires anticipation of adverse reactions

whenever a therapeutic program is instituted.

• An adverse reaction can often be minimized through use of established

protocols for premedication.

• Requistic measures include the use of epinephrine, oxygen, and adequate

fluid replacement: in some instances, vasopressors or corticosteroids drug

therapy may be warranted.

IMRAN SUFAIR.M
 ROLE OF PHARMACIST
Pharmacists should exert leadership in the development, maintenance, and

ongoing evaluation of ADR programs. They should obtain formal endorsement or

approval of such programs through appropriate committees (e.g., a pharmacy

and therapeutics committee and the executive committee of the medical staff)

and the organization’s administration. In settings where applicable, input into the

design of the pro‐gram should be obtained from the medical staff, nursing staff,

quality improvement staff, medical records department, and risk managers.

IMRAN SUFAIR.M
 The pharmacist should facilitate:

1. Analysis of each reported ADR.

2. Identification of drugs and patients at high risk for being involved in ADRs.

3. The development of policies and procedures for the ADR‐monitoring and

reporting program.

4. A description of the responsibilities and interactions of pharmacists, physicians,

nurses, risk managers, and other health professionals in the ADR program.

IMRAN SUFAIR.M
5. Use of the ADR program for educational purposes.

6. Development, maintenance, and evaluation of ADR records within the

organization.

7. The organizational dissemination and use of information obtained through the

ADR program.

8. Reporting of serious ADRs to the FDA or the manufacturer (or both), and

9.Publication and presentation of important ADRs to the medical community.

IMRAN SUFAIR.M
 CONCLUSION

Pharmacists working in community pharmacy have an added advantage of

detecting and reporting ADRs while dealing with on the counter prescriptions

and herbal products.49 In a community pharmacy, a pharmacist may not

have direct and definite patient list but the patients coming to the same

pharmacy to refill their prescription gives the pharmacist an opportunity to

detect a possible ADR that the patient might be experiencing and can help

in the management and the reporting of the said ADR.

IMRAN SUFAIR.M
Direct patient care roles for pharmacists should include patient counseling

on ADRs, identification and documentation in the patient’s medical record

of high‐risk patients, monitoring to ensure that serum drug concentrations

remain within acceptable therapeutic ranges, and adjusting doses in

appropriate patients (e.g., patients with impaired renal or hepatic function).

IMRAN SUFAIR.M
THANK YOU

IMRAN SUFAIR.M