Dusting powder for external use These are dry, free flowing preparations consisting of one or a mixture of finely powdered substances and intended for external application. The advantages of dusting powders as pharmaceutical products are • They are easy to apply. • They are pleasant to use. • They absorb skin moisture, which leads to reduced friction between skin surfaces, • Discourages bacterial growth and has a cooling effect. The disadvantages of dusting powders as pharmaceutical products are • They may block pores, causing irritation, or if applied to parietal surfaces, granulomas, fibrosis or adhesions. • There is a possibility of contamination: Starch, although an excellent dusting powder, is organic and can support microbial growth. Talc, despite being an inert compound, can be contaminated with microorganisms and must therefore always be sterilised prior to incorporation into a dusting powder. • Light fluffy powders may be inhaled by infants, causing breathing difficulties. • They are not suitable for application to broken skin. Common ingredients included in dusting powders and their properties Properties Ingredients Absorbent Bentonite BP Kaolin BP Starch BP Talc BP Dispersing and lubricating for ease of application Starch BP Talc BP Adhesives that help the powder to stick to the skin Aluminium Stearate BP Magnesium Stearate BP Zinc Stearate BP Increase 'lightness and fluffiness' Prepared Chalk BP Zinc Stearate BP White, with good covering properties Talc BP Zinc Oxide BP Clostridium tetani, Some commonly Clostridium used ingredients Therefore, such Which can cause welchii and such as talc, kaolin ingredients must tetanus and Bacillus anthracis and other natural have been sterilise gangrene. be heavily mineral before use. contaminated to substances Gangren: mengacu pada kematian jaringan tubuh karena kurangnya aliran darah atau infeksi bakteri. Kondisi ini terjadi setelah seseorang mengalami luka, infeksi, atau masalah kesehatan kronis yang memengaruhi sirkulasi darah.
Tetanus yang juga dikenal dengan lockjaw,
merupakan penyakit yang disebakan oleh tetanospasmin, yaitu sejenis neurotoksin yang diproduksi oleh Clostridium tetani yang menginfeksi sistem urat saraf dan otot sehingga saraf dan otot menjadi kaku (rigid). Common active ingredients included in dusting powders and their properties Properties Ingredients Antibakteri/ antifungal Sulphur BP Astringents Aluminium Chloride BP Tannic Acid BP Cooling antipruritic ingredients Menthol BP Thymol BP Camphor BP The label of a pharmaceutical product has many functions: To indicate clearly the contents of the container
To indicate clearly to patients how and when the
medicinal product should be taken or used To indicate clearly to patients how the product should be stored and for how long To indicate clearly to patients any warnings or cautions of which they need to be made aware. Permanent reminder!!! Some techniques of powder dust preparation •Trituration •Incorporate I •Incorporate II