TERAPI

HIPERTENSI
RESISTEN
ELFARINI
406151044
Hipertensi Resisten

• Menurut Joint National Committee (JNC 7) Hipertensi

Resisten adalah ketidakmampuan untuk mencapai
tekanan darah lebih rendah dari 140/90 mm Hg
meskipun sudah mendapatkan dosis optimal dari
tiga atau lebih obat antihipertensi, termasuk satu
diuretik.

• Menurut American Heart Association (AHA)

hipertensi resisten adalah hipertensi yang tidak
terkontrol meskipun sudah diberikan setidaknya
tiga obat antihipertensi atau hipertensi terkontrol
dengan setidaknya empat obat anti hipertensi.
 Etiologi dan Patofisiologi

• Longstanding uncontrolled hypertension

• Secondary hypertension
• Nonadherence to therapy
• Interfering medications
• Lifestyle factors

SW Tobe, R lewanczuk. Resistant hypertension. Can J Cardiol

2009;25(5):315-317
Lifestyle Factor
Management
 DAFTAR PUSTAKA
1.WHO. Raised Blood Pressure. Available from: http
://www.who.int/gho/ncd/risk_factors/blood_pressure_prevalence_text/en/. November 20, 2013
2.Yogiantoro M. Hipertensi Esensial. Dalam: Sudoyo AW, Setiyohadi B, Alwi I, Simadibrata M, Setiatii S
(editor). Buku Ajar Ilmu Penyakit Dalam. Edisi 5. Jakarta: Interna Publishing; 2009.p. 1079-85
3.Can J Cardiol Vol 25 No 5 May 2009 SW Tobe, R lewanczuk. Resistant hypertension. Can J Cardiol
2009;25(5):315-317.
4.Pierdomenico SD, Lapenna D, Bucci A, et al. Cardiovascular outcome in treated hypertensive patients
with responder, masked, false resistant, and true resistant hypertension. Am J Hypertens
2005;18:1422-8
5.Chobanian AV, Bakris GL, Black HR, et al. The Seventh Report of the Joint National Committee on
Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: The JNC 7report. JAMA
2003;289:2560-72
6.Epstein M. Resistant hypertension: Prevalence and evolving concepts. J Clin Hypertens 2007;9:2-6.
7.Pickering TG. Arterial stiffness as a cause of resistant hypertension. J Clin Hypertens 2007;9:390-5.
8.Logan AG, Perlikowski SM, Mente A, et al. High prevalence of unrecognized sleep apnoea in drug-
resistant hypertension. J Hypertens 2001;19:2271-7.
9.Padwal R, Campbell NR, Feldman RD, et al. The 2009 Canadian Hypertension Education Program
recommendations for the management of hypertension: Part I – Blood pressure
measurement,diagnosis and assessment of risk. Can J Cardiol 2009;25:279-86.
10.
Wanpen Vongpatanasin. Resistant Hypertension A Review of Diagnosis and Management. Available
From: http://jama.jamanetwork.com/ by a Anne Arundel Medical Center User on 06/11/2014