Beruflich Dokumente
Kultur Dokumente
Department of Surgery
Medical Faculty of Hasanuddin University
2012
Principles in Management of Tumors
1. Diagnosis.
2. Staging / Stadium.
3. Performance status .
4. Treatment planning.
5. Treatment Implementation.
6. Follow-up / Reconstruction / Rehabilitation.
Treatment Planning depend on :
- Histopathologic type of cancer
- Stage ( Early stage or late stage )
- Operable or Inoperable
- Curative or Palliative treatment
- Patients Performance Status
The aim of cancer treatment :
- Curative
- Paliative
Adjuvant Therapy:
- Adjuvant Surgery / Operative
- Adjuvant Chemotherapy
- Adjuvant Radiotherapy
- Adjuvant Hormonal Therapy
Operative / surgery
The mainstay of cancer treatment is surgery
Diagnostic Surgery
This type of surgery is used to get a tissue sample for
histopathologic examination
Defenitive Surgery
Defenitive surgery or Curative Surgery is done when a tumor
appears to be confined to one area and it is likely that all of the
tumor can be removed.
Preventive / prophylactic surgery
This type of surgery is done to remove body tissue that is likely
to become malignant even though there are no sign of cancer at
the time of surgery.
Debulking Surgery
Also called Cytoreductive Surgery, this type of surgery is done to
remove some but not all of the tumor
Metastasectomy
This type of surgery is done to remove the metastasis
tumor far from the primary tumor site
Palliative Surgery
This type of surgery is used to treat complication of
advanced cancer or to correct a problem that is causing
discomfort or disability
Oncologic Emergency Surgery
This type of surgery is done for life saving
- Bleeding
- Tracheal Obstruction
MELPHALAN PLICAMYCIN
Antibiotics
Antimetabolites
S
(2-6h)
G2
(2-32h) Vinca alkaloids
M Mitotic inhibitors
(0.5-2h)
Taxoids
Alkylating agents
G1
(2-h)
G0
Regimen of Chemotherapy :
- Monotherapy
- Combination therapy
ACTIVITY SAFETY
Different mechanisms of action Compatible side effects
Different mechanisms of resistance
SIDE EFFECTS OF CHEMOTHERAPY
Alopecia
Mucositis
Pulmonary fibrosis
Nausea/vomiting
Cardiotoxicity
Diarrhea
Cystitis Local reaction
Radiotherapy :
- Curative
- Paliative
Hormonal Therapy
Steroid hormone are required for the growth and function of :
- Breast, endometrium and prostat
Thank You
4 objectives in rehabilitation of patients with cancer:
- Psychosocial support
- Optimization of physical functioning
- Vocational counseling
- Optimization of social functioning
Thank You