Beruflich Dokumente
Kultur Dokumente
Resna N K
Ist sem M. Phil
Immunity
Active immunity
Post World War 2 successful live viral vaccines developed using cell
culture techniques
New technologies constantly developing:
Present and
future recombinant protein vaccines, DNA and conjugate
vaccines
IMMUNIZATION
Passive Active
Natural- Artificial-
Injection of Inoculation with
Mother to foetus microbial pathogen
antibodies or
Previous infections vaccines
The CDC's recommended immunization schedule for the general
population
Passive immunization
Introduced by Emil von Behring and Hidesaburo Kitasato
Serum
transferring
Infected animal Other animal
(get immunized)
Across the
Maternal antibodies Developing fetus
placenta
Attenuated vaccines
Purified Macromolecules as Vaccines
Capsular polysaccharide as vaccines
Inactivated exotoxins as vaccines
use in humans.
Attenuated Viruses and Bacteria Cause
Immunity Without Disease
Chemicals
Inactivation Vaccine
of pathogen production
Heat
2.Reactions vaccine or
contraindicatio due to
ns ignored dliluent
faulty contaminated
techniques
vaccine
prepared
wrong amount
incorrectly for
of diluent used
use
vaccine stored
incorrectly
3. Reactions due to hypersensitivity:
Viral vaccines symptoms may appear
prepared from within a few minutes of
embryonated eggs injection or may be
(e.g., influenza) delayed up to 2 hours
Various antibiotics
used in their
preparation
Anaphylaxis
Serum
sickness
Dangerous complication:
bronchospasm,
dyspnoea, pallor, Characterized by
hypotension and symptoms such as
collapse fever, rash, oedema
and joint pains
4. Neurological involvement:
5. Provocative reactions: