Beruflich Dokumente
Kultur Dokumente
Dulmet EM, Macchiarini P, Suc B, et al. Germ cell tumors of the mediastinum: a 30 year experience. Cancer 1993;72:1994.
Epidemiology
Travis WD. Pathology and genetics of tumours of the lung, pleura, thymus and heart. Iarc. (2004) ISBN:9283224183
Histologically, teratomas may be solid or cystic in appearance and are
often referred to as dermoid cysts if unilocular The majority of
mediastinal teratomas is composed of mature ectodermal, mesodermal,
and endodermal elements and exhibits a benign course
Moeller KH, Rosado-de-Christenson ML, Templeton PA. Mediastinal mature teratoma: imaging features. AJR Am J Roentgenol 1997;169(4):985-990.
Taniyama K, Ohta S, Suzuki H, Matsumoto M, et al. Alpha-fetoprotein-producing immature mediastinal teratoma showing rapid and massive recurrent
growth in an adult. Acta Pathol Jpn 1992;42(12):911.
Clinical presentation
Travis WD. Pathology and genetics of tumours of the lung, pleura, thymus and heart. Iarc. (2004) ISBN:9283224183
Treatment
For mature and differentiated teratomas the radical surgical removal is the
only curative treatment, because unnecessary delay may result in the
rupture of tumors or in malignant degeneration.
The prognosis after surgical removal of the tumor is good and there is no
recurrence of tumor after complete excision
Smahi M, Achir A, Chafik A, et al. Mature teratoma of the mediastinum. Ann Chir 2000;125(10):965-971.
For immature teratomas the main options are primary resection and
chemotherapy
THANK YOU…
Non surgical vs operabilitas
(TNM/evaluasi struktur)