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INTERACTIONS BETWEEN
GENES
Polygenic inheritance
PR Pr pR pr
PR Walnut Walnut Walnut Walnut
Pr Walnut Pea Walnut Pea
pR Walnut Walnut Rose Rose
pr Walnut Pea Rose Single
Comb shape in chickens
Walnut ……………………..
Pea ……………………..
Rose ……………………..
Single ……………………..
Comb shape in chickens
Walnut P_R_
Pea P_rr
Rose ppR_
Single pprr
Unusual ratios
AC Ac aC ac
AC AACC AACc AaCC AaCc
Ac AACc AAcc AaCc Aacc
aC AaCC AaCc aaCC aaCc
ac AaCc Aacc aaCc aacc
Coat colour in mice
AC Ac aC ac
AC Mousy Mousy Mousy Mousy
Ac Mousy Albino Mousy Albino
aC Mousy Mousy Black Black
ac Mousy Albino Black Albino
Coat colour in mice
Wild type A_ B_ C_
Black aa B_ C_
Chocolate aa bb C_
Cinnamon A_ bb C_
Albino _ _ _ _ cc
The more genes that interact the greater the range
of phenotypes produced
This ultimately leads to a continuous distribution
of traits where one blends into another.
Human skin pigmentation
• Initially this was thought to be controlled by
two genes P1 and P2
• These control the production of the protein
melanin